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Safety of P28GST, a Protein Derived from a Schistosome Helminth Parasite, in Patients with Crohn's Disease: A Pilot Study (ACROHNEM).
Capron M, Béghin L, Leclercq C, Labreuche J, Dendooven A, Standaert A, Delbeke M, Porcherie A, Nachury M, Boruchowicz A, Dupas JL, Fumery M, Paupard T, Catteau S, Deplanque D, Colombel JF, Desreumaux P. Capron M, et al. J Clin Med. 2019 Dec 24;9(1):41. doi: 10.3390/jcm9010041. J Clin Med. 2019. PMID: 31878146 Free PMC article.
Treatment with P28GST, a schistosome-derived enzyme, after acute colitis induction in mice: Decrease of intestinal inflammation associated with a down regulation of Th1/Th17 responses.
Sarazin A, Dendooven A, Delbeke M, Gatault S, Pagny A, Standaert A, Rousseaux C, Desreumaux P, Dubuquoy L, Capron M. Sarazin A, et al. Among authors: capron m. PLoS One. 2018 Dec 28;13(12):e0209681. doi: 10.1371/journal.pone.0209681. eCollection 2018. PLoS One. 2018. PMID: 30592734 Free PMC article.
The schistosome glutathione S-transferase P28GST, a unique helminth protein, prevents intestinal inflammation in experimental colitis through a Th2-type response with mucosal eosinophils.
Driss V, El Nady M, Delbeke M, Rousseaux C, Dubuquoy C, Sarazin A, Gatault S, Dendooven A, Riveau G, Colombel JF, Desreumaux P, Dubuquoy L, Capron M. Driss V, et al. Among authors: capron m. Mucosal Immunol. 2016 Mar;9(2):322-35. doi: 10.1038/mi.2015.62. Epub 2015 Jul 15. Mucosal Immunol. 2016. PMID: 26174763 Free PMC article.
Eosinophils in allergic reactions.
Desreumaux P, Capron M. Desreumaux P, et al. Among authors: capron m. Curr Opin Immunol. 1996 Dec;8(6):790-5. doi: 10.1016/s0952-7915(96)80006-9. Curr Opin Immunol. 1996. PMID: 8994857 Review.
434 results