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Substrate binding and inhibition of the anion exchanger 1 transporter.
Capper MJ, Yang S, Stone AC, Vatansever S, Zilberg G, Mathiharan YK, Habib R, Hutchinson K, Zhao Y, Schlessinger A, Mezei M, Osman R, Zhang B, Wacker D. Capper MJ, et al. Nat Struct Mol Biol. 2023 Oct;30(10):1495-1504. doi: 10.1038/s41594-023-01085-6. Epub 2023 Sep 7. Nat Struct Mol Biol. 2023. PMID: 37679563 Free PMC article.
Structural pharmacology and therapeutic potential of 5-methoxytryptamines.
Warren AL, Lankri D, Cunningham MJ, Serrano IC, Parise LF, Kruegel AC, Duggan P, Zilberg G, Capper MJ, Havel V, Russo SJ, Sames D, Wacker D. Warren AL, et al. Among authors: capper mj. Nature. 2024 May 8. doi: 10.1038/s41586-024-07403-2. Online ahead of print. Nature. 2024. PMID: 38720072
Antimalarial 4(1H)-pyridones bind to the Qi site of cytochrome bc1.
Capper MJ, O'Neill PM, Fisher N, Strange RW, Moss D, Ward SA, Berry NG, Lawrenson AS, Hasnain SS, Biagini GA, Antonyuk SV. Capper MJ, et al. Proc Natl Acad Sci U S A. 2015 Jan 20;112(3):755-60. doi: 10.1073/pnas.1416611112. Epub 2015 Jan 6. Proc Natl Acad Sci U S A. 2015. PMID: 25564664 Free PMC article.