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Reactive oxygen species modulate macrophage immunosuppressive phenotype through the up-regulation of PD-L1.
Roux C, Jafari SM, Shinde R, Duncan G, Cescon DW, Silvester J, Chu MF, Hodgson K, Berger T, Wakeham A, Palomero L, Garcia-Valero M, Pujana MA, Mak TW, McGaha TL, Cappello P, Gorrini C. Roux C, et al. Among authors: cappello p. Proc Natl Acad Sci U S A. 2019 Mar 5;116(10):4326-4335. doi: 10.1073/pnas.1819473116. Epub 2019 Feb 15. Proc Natl Acad Sci U S A. 2019. PMID: 30770442 Free PMC article.
Role of Nek2 on centrosome duplication and aneuploidy in breast cancer cells.
Cappello P, Blaser H, Gorrini C, Lin DC, Elia AJ, Wakeham A, Haider S, Boutros PC, Mason JM, Miller NA, Youngson B, Done SJ, Mak TW. Cappello P, et al. Oncogene. 2014 May 1;33(18):2375-84. doi: 10.1038/onc.2013.183. Epub 2013 May 27. Oncogene. 2014. PMID: 23708664 Free article.
AhR controls redox homeostasis and shapes the tumor microenvironment in BRCA1-associated breast cancer.
Kubli SP, Bassi C, Roux C, Wakeham A, Göbl C, Zhou W, Jafari SM, Snow B, Jones L, Palomero L, Thu KL, Cassetta L, Soong D, Berger T, Ramachandran P, Baniasadi SP, Duncan G, Lindzen M, Yarden Y, Herranz C, Lazaro C, Chu MF, Haight J, Tinto P, Silvester J, Cescon DW, Petit A, Pettersson S, Pollard JW, Mak TW, Pujana MA, Cappello P, Gorrini C. Kubli SP, et al. Among authors: cappello p. Proc Natl Acad Sci U S A. 2019 Feb 26;116(9):3604-3613. doi: 10.1073/pnas.1815126116. Epub 2019 Feb 7. Proc Natl Acad Sci U S A. 2019. PMID: 30733286 Free PMC article.
IL17A critically shapes the transcriptional program of fibroblasts in pancreatic cancer and switches on their protumorigenic functions.
Mucciolo G, Curcio C, Roux C, Li WY, Capello M, Curto R, Chiarle R, Giordano D, Satolli MA, Lawlor R, Scarpa A, Lukac P, Stakheev D, Provero P, Vannucci L, Mak TW, Novelli F, Cappello P. Mucciolo G, et al. Among authors: cappello p. Proc Natl Acad Sci U S A. 2021 Feb 9;118(6):e2020395118. doi: 10.1073/pnas.2020395118. Proc Natl Acad Sci U S A. 2021. PMID: 33526692 Free PMC article.
Endogenous glutamine decrease is associated with pancreatic cancer progression.
Roux C, Riganti C, Borgogno SF, Curto R, Curcio C, Catanzaro V, Digilio G, Padovan S, Puccinelli MP, Isabello M, Aime S, Cappello P, Novelli F. Roux C, et al. Among authors: cappello p. Oncotarget. 2017 Aug 24;8(56):95361-95376. doi: 10.18632/oncotarget.20545. eCollection 2017 Nov 10. Oncotarget. 2017. PMID: 29221133 Free PMC article.
The dark side of immunotherapy: pancreatic cancer.
Mucciolo G, Roux C, Scagliotti A, Brugiapaglia S, Novelli F, Cappello P. Mucciolo G, et al. Among authors: cappello p. Cancer Drug Resist. 2020 May 11;3(3):491-520. doi: 10.20517/cdr.2020.13. eCollection 2020. Cancer Drug Resist. 2020. PMID: 35582441 Free PMC article. Review.
99 results