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Pimozide Alleviates Hyperglycemia in Diet-Induced Obesity by Inhibiting Skeletal Muscle Ketone Oxidation.
Al Batran R, Gopal K, Capozzi ME, Chahade JJ, Saleme B, Tabatabaei-Dakhili SA, Greenwell AA, Niu J, Almutairi M, Byrne NJ, Masson G, Kim R, Eaton F, Mulvihill EE, Garneau L, Masters AR, Desta Z, Velázquez-Martínez CA, Aguer C, Crawford PA, Sutendra G, Campbell JE, Dyck JRB, Ussher JR. Al Batran R, et al. Among authors: capozzi me. Cell Metab. 2020 May 5;31(5):909-919.e8. doi: 10.1016/j.cmet.2020.03.017. Epub 2020 Apr 9. Cell Metab. 2020. PMID: 32275862 Free article.
β Cell tone is defined by proglucagon peptides through cAMP signaling.
Capozzi ME, Svendsen B, Encisco SE, Lewandowski SL, Martin MD, Lin H, Jaffe JL, Coch RW, Haldeman JM, MacDonald PE, Merrins MJ, D'Alessio DA, Campbell JE. Capozzi ME, et al. JCI Insight. 2019 Mar 7;4(5):e126742. doi: 10.1172/jci.insight.126742. eCollection 2019 Mar 7. JCI Insight. 2019. PMID: 30720465 Free PMC article.
Glucagon lowers glycemia when β-cells are active.
Capozzi ME, Wait JB, Koech J, Gordon AN, Coch RW, Svendsen B, Finan B, D'Alessio DA, Campbell JE. Capozzi ME, et al. JCI Insight. 2019 Jul 23;5(16):e129954. doi: 10.1172/jci.insight.129954. JCI Insight. 2019. PMID: 31335319 Free PMC article.
41 results