Caplan MJ - Search Results

1

The C-terminal tail of polycystin-1 suppresses cystic disease in a mitochondrial enzyme-dependent fashion.

Onuchic L, Padovano V, Schena G, Rajendran V, Dong K, Shi X, Pandya R, Rai V, Gresko NP, Ahmed O, Lam TT, Wang W, Shen H, Somlo S, Caplan MJ. Onuchic L, et al. Among authors: caplan mj. Nat Commun. 2023 Mar 30;14(1):1790. doi: 10.1038/s41467-023-37449-1. Nat Commun. 2023. PMID: 36997516 Free PMC article.

2

The Polycystin Complex Reveals Its Complexity.

Padovano V, Caplan MJ. Padovano V, et al. Among authors: caplan mj. Biochemistry. 2018 Dec 26;57(51):6917-6918. doi: 10.1021/acs.biochem.8b01205. Epub 2018 Dec 12. Biochemistry. 2018. PMID: 30540438 No abstract available.

3

A cut above (and below): Protein cleavage in the regulation of polycystin trafficking and signaling.

Padovano V, Mistry K, Merrick D, Gresko N, Caplan MJ. Padovano V, et al. Among authors: caplan mj. Cell Signal. 2020 Aug;72:109634. doi: 10.1016/j.cellsig.2020.109634. Epub 2020 Apr 10. Cell Signal. 2020. PMID: 32283256 Free PMC article. Review.

4

Polycystin-1 distribution is modulated by polycystin-2 expression in mammalian cells.

Grimm DH, Cai Y, Chauvet V, Rajendran V, Zeltner R, Geng L, Avner ED, Sweeney W, Somlo S, Caplan MJ. Grimm DH, et al. Among authors: caplan mj. J Biol Chem. 2003 Sep 19;278(38):36786-93. doi: 10.1074/jbc.M306536200. Epub 2003 Jul 2. J Biol Chem. 2003. PMID: 12840011 Free article.

5

Mechanical stimuli induce cleavage and nuclear translocation of the polycystin-1 C terminus.

Chauvet V, Tian X, Husson H, Grimm DH, Wang T, Hiesberger T, Igarashi P, Bennett AM, Ibraghimov-Beskrovnaya O, Somlo S, Caplan MJ. Chauvet V, et al. Among authors: caplan mj. J Clin Invest. 2004 Nov;114(10):1433-43. doi: 10.1172/JCI21753. J Clin Invest. 2004. PMID: 15545994 Free PMC article.

6

The C-terminal tail of the polycystin-1 protein interacts with the Na,K-ATPase alpha-subunit.

Zatti A, Chauvet V, Rajendran V, Kimura T, Pagel P, Caplan MJ. Zatti A, et al. Among authors: caplan mj. Mol Biol Cell. 2005 Nov;16(11):5087-93. doi: 10.1091/mbc.e05-03-0200. Epub 2005 Aug 17. Mol Biol Cell. 2005. PMID: 16107561 Free PMC article.

7

Polycystin-2 regulates proliferation and branching morphogenesis in kidney epithelial cells.

Grimm DH, Karihaloo A, Cai Y, Somlo S, Cantley LG, Caplan MJ. Grimm DH, et al. Among authors: caplan mj. J Biol Chem. 2006 Jan 6;281(1):137-44. doi: 10.1074/jbc.M507845200. Epub 2005 Nov 8. J Biol Chem. 2006. PMID: 16278216 Free article.

8

Polycystin-1 C-terminal cleavage is modulated by polycystin-2 expression.

Bertuccio CA, Chapin HC, Cai Y, Mistry K, Chauvet V, Somlo S, Caplan MJ. Bertuccio CA, et al. Among authors: caplan mj. J Biol Chem. 2009 Jul 31;284(31):21011-26. doi: 10.1074/jbc.M109.017756. Epub 2009 Jun 2. J Biol Chem. 2009. PMID: 19491093 Free PMC article.

9

Polycystin-1 surface localization is stimulated by polycystin-2 and cleavage at the G protein-coupled receptor proteolytic site.

Chapin HC, Rajendran V, Caplan MJ. Chapin HC, et al. Among authors: caplan mj. Mol Biol Cell. 2010 Dec;21(24):4338-48. doi: 10.1091/mbc.E10-05-0407. Epub 2010 Oct 27. Mol Biol Cell. 2010. PMID: 20980620 Free PMC article.

10

The γ-secretase cleavage product of polycystin-1 regulates TCF and CHOP-mediated transcriptional activation through a p300-dependent mechanism.

Merrick D, Chapin H, Baggs JE, Yu Z, Somlo S, Sun Z, Hogenesch JB, Caplan MJ. Merrick D, et al. Among authors: caplan mj. Dev Cell. 2012 Jan 17;22(1):197-210. doi: 10.1016/j.devcel.2011.10.028. Epub 2011 Dec 15. Dev Cell. 2012. PMID: 22178500 Free PMC article.

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