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Isolation and characterization of soluble human full-length TDP-43 associated with neurodegeneration.
Vivoli Vega M, Nigro A, Luti S, Capitini C, Fani G, Gonnelli L, Boscaro F, Chiti F. Vivoli Vega M, et al. Among authors: capitini c. FASEB J. 2019 Oct;33(10):10780-10793. doi: 10.1096/fj.201900474R. Epub 2019 Jul 9. FASEB J. 2019. PMID: 31287959
Analyses with dynamic light scattering and SEC revealed that the protein is a dimer.-Vivoli Vega, M., Nigro, A., Luti, S., Capitini, C., Fani, G., Gonnelli, L., Boscaro, F., Chiti, F. Isolation and characterization of soluble human full-length TDP-43 associated with …
Analyses with dynamic light scattering and SEC revealed that the protein is a dimer.-Vivoli Vega, M., Nigro, A., Luti, S., Capitini, …
Quantitative assessment of the degradation of aggregated TDP-43 mediated by the ubiquitin proteasome system and macroautophagy.
Cascella R, Fani G, Capitini C, Rusmini P, Poletti A, Cecchi C, Chiti F. Cascella R, et al. Among authors: capitini c. FASEB J. 2017 Dec;31(12):5609-5624. doi: 10.1096/fj.201700292RR. Epub 2017 Aug 25. FASEB J. 2017. PMID: 28842427 Free article.
We also found that the proteasome and macroautophagy-degradable pools of TDP-43 are fully distinguishable, rather than in equilibrium between them on the time scale required for degradation, and that a significant crosstalk exists between the 2 degradation processes.-Cascella, R. …
We also found that the proteasome and macroautophagy-degradable pools of TDP-43 are fully distinguishable, rather than in equilibrium betwee …
Structural differences between toxic and nontoxic HypF-N oligomers.
Capitini C, Patel JR, Natalello A, D'Andrea C, Relini A, Jarvis JA, Birolo L, Peduzzo A, Vendruscolo M, Matteini P, Dobson CM, De Simone A, Chiti F. Capitini C, et al. Chem Commun (Camb). 2018 Aug 11;54(62):8637-8640. doi: 10.1039/c8cc03446j. Epub 2018 Jul 18. Chem Commun (Camb). 2018. PMID: 30020284
94 results