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CBFA2T3-GLIS2-dependent pediatric acute megakaryoblastic leukemia is driven by GLIS2 and sensitive to navitoclax.
Neault M, Lebert-Ghali CÉ, Fournier M, Capdevielle C, Garfinkle EAR, Obermayer A, Cotton A, Boulay K, Sawchyn C, St-Amand S, Nguyen KH, Assaf B, Mercier FE, Delisle JS, Drobetsky EA, Hulea L, Shaw TI, Zuber J, Gruber TA, Melichar HJ, Mallette FA. Neault M, et al. Among authors: capdevielle c. Cell Rep. 2023 Sep 26;42(9):113084. doi: 10.1016/j.celrep.2023.113084. Epub 2023 Sep 15. Cell Rep. 2023. PMID: 37716355 Free article.
An EZH2 blocker sensitizes histone mutated diffuse midline glioma to cholesterol metabolism inhibitors through an off-target effect.
Rahal F, Capdevielle C, Rousseau B, Izotte J, Dupuy JW, Cappellen D, Chotard G, Ménard M, Charpentier J, Jecko V, Caumont C, Gimbert E, Grosset CF, Hagedorn M. Rahal F, et al. Among authors: capdevielle c. Neurooncol Adv. 2022 Mar 1;4(1):vdac018. doi: 10.1093/noajnl/vdac018. eCollection 2022 Jan-Dec. Neurooncol Adv. 2022. PMID: 35300150 Free PMC article.
Scaffolding proteins in pediatric glioma.
Capdevielle C, Hagedorn M. Capdevielle C, et al. Aging (Albany NY). 2021 Oct 26;13(20):23440-23441. doi: 10.18632/aging.203659. Epub 2021 Oct 26. Aging (Albany NY). 2021. PMID: 34705668 Free PMC article. No abstract available.
HDAC inhibition induces expression of scaffolding proteins critical for tumor progression in pediatric glioma: focus on EBP50 and IRSp53.
Capdevielle C, Desplat A, Charpentier J, Sagliocco F, Thiebaud P, Thézé N, Fédou S, Hooks KB, Silvestri R, Guyonnet-Duperat V, Petrel M, Raymond AA, Dupuy JW, Grosset CF, Hagedorn M. Capdevielle C, et al. Neuro Oncol. 2020 Apr 15;22(4):550-562. doi: 10.1093/neuonc/noz215. Neuro Oncol. 2020. PMID: 31711240 Free PMC article.