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The plant product quinic acid activates Ca2+ -dependent mitochondrial function and promotes insulin secretion from pancreatic beta cells.
Heikkilä E, Hermant A, Thevenet J, Bermont F, Kulkarni SS, Ratajczak J, Santo-Domingo J, Dioum EH, Canto C, Barron D, Wiederkehr A, De Marchi U. Heikkilä E, et al. Among authors: canto c. Br J Pharmacol. 2019 Sep;176(17):3250-3263. doi: 10.1111/bph.14757. Epub 2019 Jul 15. Br J Pharmacol. 2019. PMID: 31166006 Free PMC article.
The molecular targets of resveratrol.
Kulkarni SS, Cantó C. Kulkarni SS, et al. Among authors: canto c. Biochim Biophys Acta. 2015 Jun;1852(6):1114-23. doi: 10.1016/j.bbadis.2014.10.005. Epub 2014 Oct 12. Biochim Biophys Acta. 2015. PMID: 25315298 Free article. Review.
SIRT1 enhances glucose tolerance by potentiating brown adipose tissue function.
Boutant M, Joffraud M, Kulkarni SS, García-Casarrubios E, García-Roves PM, Ratajczak J, Fernández-Marcos PJ, Valverde AM, Serrano M, Cantó C. Boutant M, et al. Among authors: canto c. Mol Metab. 2014 Dec 18;4(2):118-31. doi: 10.1016/j.molmet.2014.12.008. eCollection 2015 Feb. Mol Metab. 2014. PMID: 25685699 Free PMC article.
Coordinated activation of mitochondrial respiration and exocytosis mediated by PKC signaling in pancreatic β cells.
Santo-Domingo J, Chareyron I, Dayon L, Núñez Galindo A, Cominetti O, Pilar Giner Giménez M, De Marchi U, Canto C, Kussmann M, Wiederkehr A. Santo-Domingo J, et al. Among authors: canto c. FASEB J. 2017 Mar;31(3):1028-1045. doi: 10.1096/fj.201600837R. Epub 2016 Dec 7. FASEB J. 2017. PMID: 27927723
The data set was enriched for proteins that are involved in gene expression, cytoskeleton remodeling, secretory vesicle transport, and exocytosis. Interactome analysis identified PKC, C-Raf, and ERK1/2 as the central phosphointeraction cluster. Prevention of ERK1/2 signali …
The data set was enriched for proteins that are involved in gene expression, cytoskeleton remodeling, secretory vesicle transport, and exocy …
Mfn2 is critical for brown adipose tissue thermogenic function.
Boutant M, Kulkarni SS, Joffraud M, Ratajczak J, Valera-Alberni M, Combe R, Zorzano A, Cantó C. Boutant M, et al. Among authors: canto c. EMBO J. 2017 Jun 1;36(11):1543-1558. doi: 10.15252/embj.201694914. Epub 2017 Mar 27. EMBO J. 2017. PMID: 28348166 Free PMC article.
151 results