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The Glutathione Metabolite γ-Glutamyl-Glutamate Partially Activates Glutamate NMDA Receptors in Central Neurons With Higher Efficacy for GluN2B-Containing Receptors.
Sebih F, Mokrane N, Fontanel P, Kayatekin M, Kaabeche M, Guiramand J, Cohen-Solal C, Cens T, Rousset M, Charnet P, De Jésus Ferreira MC, Thibaud JB, Ménard C, Cantel S, Rolland V, Vignes M, Roussel J. Sebih F, et al. Among authors: cantel s. Front Pharmacol. 2022 Jan 3;12:794680. doi: 10.3389/fphar.2021.794680. eCollection 2021. Front Pharmacol. 2022. PMID: 35046818 Free PMC article.
The novel nonapeptide acein targets angiotensin converting enzyme in the brain and induces dopamine release.
Neasta J, Valmalle C, Coyne AC, Carnazzi E, Subra G, Galleyrand JC, Gagne D, M'Kadmi C, Bernad N, Bergé G, Cantel S, Marin P, Marie J, Banères JL, Kemel ML, Daugé V, Puget K, Martinez J. Neasta J, et al. Among authors: cantel s. Br J Pharmacol. 2016 Apr;173(8):1314-28. doi: 10.1111/bph.13424. Epub 2016 Mar 8. Br J Pharmacol. 2016. PMID: 27027724 Free PMC article.
Design and characterization of a triazole-based growth hormone secretagogue receptor modulator inhibiting the glucoregulatory and feeding actions of ghrelin.
Péraldi-Roux S, Bayle M, M'Kadmi C, Damian M, Vaillé J, Fernandez G, Cornejo MP, Marie J, Banères JL, Ben Haj Salah K, Fehrentz JA, Cantel S, Perello M, Denoyelle S, Oiry C, Neasta J. Péraldi-Roux S, et al. Among authors: cantel s. Biochem Pharmacol. 2022 Aug;202:115114. doi: 10.1016/j.bcp.2022.115114. Epub 2022 May 31. Biochem Pharmacol. 2022. PMID: 35659880
Development of Nonpeptidic Inverse Agonists of the Ghrelin Receptor (GHSR) Based on the 1,2,4-Triazole Scaffold.
Haj Salah KB, Maingot M, Blayo AL, M'Kadmi C, Damian M, Mary S, Cantel S, Neasta J, Oiry C, Péraldi-Roux S, Fernandez G, Romero GG, Perello M, Marie J, Banères JL, Fehrentz JA, Denoyelle S. Haj Salah KB, et al. Among authors: cantel s. J Med Chem. 2020 Oct 8;63(19):10796-10815. doi: 10.1021/acs.jmedchem.9b02122. Epub 2020 Sep 21. J Med Chem. 2020. PMID: 32882134
Circulating ghrelin crosses the blood-cerebrospinal fluid barrier via growth hormone secretagogue receptor dependent and independent mechanisms.
Uriarte M, De Francesco PN, Fernández G, Castrogiovanni D, D'Arcangelo M, Imbernon M, Cantel S, Denoyelle S, Fehrentz JA, Praetorius J, Prevot V, Perello M. Uriarte M, et al. Among authors: cantel s. Mol Cell Endocrinol. 2021 Dec 1;538:111449. doi: 10.1016/j.mce.2021.111449. Epub 2021 Aug 31. Mol Cell Endocrinol. 2021. PMID: 34478806
GHSR controls food deprivation-induced activation of CRF neurons of the hypothalamic paraventricular nucleus in a LEAP2-dependent manner.
Fernandez G, Cabral A, De Francesco PN, Uriarte M, Reynaldo M, Castrogiovanni D, Zubiría G, Giovambattista A, Cantel S, Denoyelle S, Fehrentz JA, Tolle V, Schiöth HB, Perello M. Fernandez G, et al. Among authors: cantel s. Cell Mol Life Sci. 2022 May 4;79(5):277. doi: 10.1007/s00018-022-04302-5. Cell Mol Life Sci. 2022. PMID: 35504998
45 results