Cano-Muñoz M - Search Results

1

Loss of stability and unfolding cooperativity in hPGK1 upon gradual structural perturbation of its N-terminal domain hydrophobic core.

Pacheco-García JL, Loginov DS, Naganathan AN, Vankova P, Cano-Muñoz M, Man P, Pey AL. Pacheco-García JL, et al. Among authors: cano munoz m. Sci Rep. 2022 Oct 13;12(1):17200. doi: 10.1038/s41598-022-22088-1. Sci Rep. 2022. PMID: 36229482 Free PMC article.

2

Naturally-Occurring Rare Mutations Cause Mild to Catastrophic Effects in the Multifunctional and Cancer-Associated NQO1 Protein.

Pacheco-García JL, Cano-Muñoz M, Sánchez-Ramos I, Salido E, Pey AL. Pacheco-García JL, et al. Among authors: cano munoz m. J Pers Med. 2020 Nov 3;10(4):207. doi: 10.3390/jpm10040207. J Pers Med. 2020. PMID: 33153185 Free PMC article.

3

Conformational flexibility of the conserved hydrophobic pocket of HIV-1 gp41. Implications for the discovery of small-molecule fusion inhibitors.

Cano-Muñoz M, Jurado S, Morel B, Conejero-Lara F. Cano-Muñoz M, et al. Int J Biol Macromol. 2021 Dec 1;192:90-99. doi: 10.1016/j.ijbiomac.2021.09.198. Epub 2021 Oct 5. Int J Biol Macromol. 2021. PMID: 34619276 Free article.

4

Extremely Thermostabilizing Core Mutations in Coiled-Coil Mimetic Proteins of HIV-1 gp41 Produce Diverse Effects on Target Binding but Do Not Affect Their Inhibitory Activity.

Cano-Muñoz M, Cesaro S, Morel B, Lucas J, Moog C, Conejero-Lara F. Cano-Muñoz M, et al. Biomolecules. 2021 Apr 12;11(4):566. doi: 10.3390/biom11040566. Biomolecules. 2021. PMID: 33921495 Free PMC article.

5

Thermodynamic dissection of the interface between HIV-1 gp41 heptad repeats reveals cooperative interactions and allosteric effects.

Jurado S, Cano-Muñoz M, Polo-Megías D, Conejero-Lara F, Morel B. Jurado S, et al. Arch Biochem Biophys. 2020 Jul 30;688:108401. doi: 10.1016/j.abb.2020.108401. Epub 2020 May 4. Arch Biochem Biophys. 2020. PMID: 32376316

6

Structural and Thermodynamic Analysis of HIV-1 Fusion Inhibition Using Small gp41 Mimetic Proteins.

Jurado S, Cano-Muñoz M, Morel B, Standoli S, Santarossa E, Moog C, Schmidt S, Laumond G, Cámara-Artigas A, Conejero-Lara F. Jurado S, et al. J Mol Biol. 2019 Aug 9;431(17):3091-3106. doi: 10.1016/j.jmb.2019.06.022. Epub 2019 Jun 27. J Mol Biol. 2019. PMID: 31255705

7

Probing Vulnerability of the gp41 C-Terminal Heptad Repeat as Target for Miniprotein HIV Inhibitors.

Jurado S, Moog C, Cano-Muñoz M, Schmidt S, Laumond G, Ruocco V, Standoli S, Polo-Megías D, Conejero-Lara F, Morel B. Jurado S, et al. J Mol Biol. 2020 Sep 18;432(20):5577-5592. doi: 10.1016/j.jmb.2020.08.010. Epub 2020 Aug 19. J Mol Biol. 2020. PMID: 32822695

8

Conformational Stabilization of Gp41-Mimetic Miniproteins Opens Up New Ways of Inhibiting HIV-1 Fusion.

Cano-Muñoz M, Lucas J, Lin LY, Cesaro S, Moog C, Conejero-Lara F. Cano-Muñoz M, et al. Int J Mol Sci. 2022 Mar 3;23(5):2794. doi: 10.3390/ijms23052794. Int J Mol Sci. 2022. PMID: 35269936 Free PMC article.

9

Novel chimeric proteins mimicking SARS-CoV-2 spike epitopes with broad inhibitory activity.

Cano-Muñoz M, Polo-Megías D, Cámara-Artigas A, Gavira JA, López-Rodríguez MJ, Laumond G, Schmidt S, Demiselle J, Bahram S, Moog C, Conejero-Lara F. Cano-Muñoz M, et al. Int J Biol Macromol. 2022 Dec 1;222(Pt B):2467-2478. doi: 10.1016/j.ijbiomac.2022.10.031. Epub 2022 Oct 8. Int J Biol Macromol. 2022. PMID: 36220405 Free PMC article.

10

Oleanolic Acid Derivatives as Potential Inhibitors of HIV-1 Protease.

Medina-O'Donnell M, Rivas F, Reyes-Zurita FJ, Cano-Muñoz M, Martinez A, Lupiañez JA, Parra A. Medina-O'Donnell M, et al. J Nat Prod. 2019 Oct 25;82(10):2886-2896. doi: 10.1021/acs.jnatprod.9b00649. Epub 2019 Oct 16. J Nat Prod. 2019. PMID: 31617361

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