Campisi J - Search Results

1

Rutin is a potent senomorphic agent to target senescent cells and can improve chemotherapeutic efficacy.

Liu H, Xu Q, Wufuer H, Li Z, Sun R, Jiang Z, Dou X, Fu Q, Campisi J, Sun Y. Liu H, et al. Among authors: campisi j. Aging Cell. 2024 Jan;23(1):e13921. doi: 10.1111/acel.13921. Epub 2023 Jul 20. Aging Cell. 2024. PMID: 37475161 Free PMC article.

2

Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor.

Coppé JP, Patil CK, Rodier F, Sun Y, Muñoz DP, Goldstein J, Nelson PS, Desprez PY, Campisi J. Coppé JP, et al. Among authors: campisi j. PLoS Biol. 2008 Dec 2;6(12):2853-68. doi: 10.1371/journal.pbio.0060301. PLoS Biol. 2008. PMID: 19053174 Free PMC article. Clinical Trial.

3

Glucocorticoids suppress selected components of the senescence-associated secretory phenotype.

Laberge RM, Zhou L, Sarantos MR, Rodier F, Freund A, de Keizer PL, Liu S, Demaria M, Cong YS, Kapahi P, Desprez PY, Hughes RE, Campisi J. Laberge RM, et al. Among authors: campisi j. Aging Cell. 2012 Aug;11(4):569-78. doi: 10.1111/j.1474-9726.2012.00818.x. Epub 2012 Apr 17. Aging Cell. 2012. PMID: 22404905 Free PMC article.

4

Treatment-induced damage to the tumor microenvironment promotes prostate cancer therapy resistance through WNT16B.

Sun Y, Campisi J, Higano C, Beer TM, Porter P, Coleman I, True L, Nelson PS. Sun Y, et al. Among authors: campisi j. Nat Med. 2012 Sep;18(9):1359-68. doi: 10.1038/nm.2890. Nat Med. 2012. PMID: 22863786 Free PMC article.

5

MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation.

Laberge RM, Sun Y, Orjalo AV, Patil CK, Freund A, Zhou L, Curran SC, Davalos AR, Wilson-Edell KA, Liu S, Limbad C, Demaria M, Li P, Hubbard GB, Ikeno Y, Javors M, Desprez PY, Benz CC, Kapahi P, Nelson PS, Campisi J. Laberge RM, et al. Among authors: campisi j. Nat Cell Biol. 2015 Aug;17(8):1049-61. doi: 10.1038/ncb3195. Epub 2015 Jul 6. Nat Cell Biol. 2015. PMID: 26147250 Free PMC article.

6

Analysis of individual cells identifies cell-to-cell variability following induction of cellular senescence.

Wiley CD, Flynn JM, Morrissey C, Lebofsky R, Shuga J, Dong X, Unger MA, Vijg J, Melov S, Campisi J. Wiley CD, et al. Among authors: campisi j. Aging Cell. 2017 Oct;16(5):1043-1050. doi: 10.1111/acel.12632. Epub 2017 Jul 11. Aging Cell. 2017. PMID: 28699239 Free PMC article.

7

Acute myeloid leukemia induces protumoral p16INK4a-driven senescence in the bone marrow microenvironment.

Abdul-Aziz AM, Sun Y, Hellmich C, Marlein CR, Mistry J, Forde E, Piddock RE, Shafat MS, Morfakis A, Mehta T, Di Palma F, Macaulay I, Ingham CJ, Haestier A, Collins A, Campisi J, Bowles KM, Rushworth SA. Abdul-Aziz AM, et al. Among authors: campisi j. Blood. 2019 Jan 31;133(5):446-456. doi: 10.1182/blood-2018-04-845420. Epub 2018 Nov 6. Blood. 2019. PMID: 30401703 Free PMC article.

8

Targetable mechanisms driving immunoevasion of persistent senescent cells link chemotherapy-resistant cancer to aging.

Muñoz DP, Yannone SM, Daemen A, Sun Y, Vakar-Lopez F, Kawahara M, Freund AM, Rodier F, Wu JD, Desprez PY, Raulet DH, Nelson PS, van 't Veer LJ, Campisi J, Coppé JP. Muñoz DP, et al. Among authors: campisi j. JCI Insight. 2019 Jun 11;5(14):e124716. doi: 10.1172/jci.insight.124716. JCI Insight. 2019. PMID: 31184599 Free PMC article.

9

Targeting amphiregulin (AREG) derived from senescent stromal cells diminishes cancer resistance and averts programmed cell death 1 ligand (PD-L1)-mediated immunosuppression.

Xu Q, Long Q, Zhu D, Fu D, Zhang B, Han L, Qian M, Guo J, Xu J, Cao L, Chin YE, Coppé JP, Lam EW, Campisi J, Sun Y. Xu Q, et al. Among authors: campisi j. Aging Cell. 2019 Dec;18(6):e13027. doi: 10.1111/acel.13027. Epub 2019 Sep 7. Aging Cell. 2019. PMID: 31493351 Free PMC article.

10

Inhibition of USP7 activity selectively eliminates senescent cells in part via restoration of p53 activity.

He Y, Li W, Lv D, Zhang X, Zhang X, Ortiz YT, Budamagunta V, Campisi J, Zheng G, Zhou D. He Y, et al. Among authors: campisi j. Aging Cell. 2020 Mar;19(3):e13117. doi: 10.1111/acel.13117. Epub 2020 Feb 16. Aging Cell. 2020. PMID: 32064756 Free PMC article.

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