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The Δ133p53β isoform promotes an immunosuppressive environment leading to aggressive prostate cancer.
Kazantseva M, Mehta S, Eiholzer RA, Gimenez G, Bowie S, Campbell H, Reily-Bell AL, Roth I, Ray S, Drummond CJ, Reid G, Joruiz SM, Wiles A, Morrin HR, Reader KL, Hung NA, Baird MA, Slatter TL, Braithwaite AW. Kazantseva M, et al. Among authors: campbell h. Cell Death Dis. 2019 Aug 20;10(9):631. doi: 10.1038/s41419-019-1861-1. Cell Death Dis. 2019. PMID: 31431617 Free PMC article.
Hyperproliferation, cancer, and inflammation in mice expressing a Δ133p53-like isoform.
Slatter TL, Hung N, Campbell H, Rubio C, Mehta R, Renshaw P, Williams G, Wilson M, Engelmann A, Jeffs A, Royds JA, Baird MA, Braithwaite AW. Slatter TL, et al. Among authors: campbell h. Blood. 2011 May 12;117(19):5166-77. doi: 10.1182/blood-2010-11-321851. Epub 2011 Mar 16. Blood. 2011. PMID: 21411755 Free article.
∆133p53 isoform promotes tumour invasion and metastasis via interleukin-6 activation of JAK-STAT and RhoA-ROCK signalling.
Campbell H, Fleming N, Roth I, Mehta S, Wiles A, Williams G, Vennin C, Arsic N, Parkin A, Pajic M, Munro F, McNoe L, Black M, McCall J, Slatter TL, Timpson P, Reddel R, Roux P, Print C, Baird MA, Braithwaite AW. Campbell H, et al. Nat Commun. 2018 Jan 17;9(1):254. doi: 10.1038/s41467-017-02408-0. Nat Commun. 2018. PMID: 29343721 Free PMC article.
Adaptive homeostasis and the p53 isoform network.
Mehta S, Campbell H, Drummond CJ, Li K, Murray K, Slatter T, Bourdon JC, Braithwaite AW. Mehta S, et al. Among authors: campbell h. EMBO Rep. 2021 Dec 6;22(12):e53085. doi: 10.15252/embr.202153085. Epub 2021 Nov 15. EMBO Rep. 2021. PMID: 34779563 Free PMC article. Review.
Does Δ133p53 isoform trigger inflammation and autoimmunity?
Campbell HG, Slatter TL, Jeffs A, Mehta R, Rubio C, Baird M, Braithwaite AW. Campbell HG, et al. Cell Cycle. 2012 Feb 1;11(3):446-50. doi: 10.4161/cc.11.3.19054. Epub 2012 Feb 1. Cell Cycle. 2012. PMID: 22262184
Regulation of the interferon-gamma (IFN-γ) pathway by p63 and Δ133p53 isoform in different breast cancer subtypes.
Mehta SY, Morten BC, Antony J, Henderson L, Lasham A, Campbell H, Cunliffe H, Horsfield JA, Reddel RR, Avery-Kiejda KA, Print CG, Braithwaite AW. Mehta SY, et al. Among authors: campbell h. Oncotarget. 2018 Jun 26;9(49):29146-29161. doi: 10.18632/oncotarget.25635. eCollection 2018 Jun 26. Oncotarget. 2018. PMID: 30018742 Free PMC article.
1,862 results