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In vitro Leishmanicidal and Trypanosomicidal Properties of Imidazole-Containing Azine and Benzoazine Derivatives.
Martín-Montes Á, Kolodová K, Marín C, Rosales-Lombardo MJ, Sánchez-Moreno M, de Andrés-Gordo L, Cano C, Campayo L, Gómez-Muñoz A, Sanz AM, Yunta MJR. Martín-Montes Á, et al. Among authors: campayo l. ChemMedChem. 2021 Dec 6;16(23):3600-3614. doi: 10.1002/cmdc.202100413. Epub 2021 Oct 19. ChemMedChem. 2021. PMID: 34665510 Free PMC article.
Efficient inhibition of iron superoxide dismutase and of Trypanosoma cruzi growth by benzo[g]phthalazine derivatives functionalized with one or two imidazole rings.
Sanz AM, Gómez-Contreras F, Navarro P, Sánchez-Moreno M, Boutaleb-Charki S, Campuzano J, Pardo M, Osuna A, Cano C, Yunta MJ, Campayo L. Sanz AM, et al. Among authors: campayo l. J Med Chem. 2008 Mar 27;51(6):1962-6. doi: 10.1021/jm701179m. Epub 2008 Feb 23. J Med Chem. 2008. PMID: 18293910
In vivo trypanosomicidal activity of imidazole- or pyrazole-based benzo[g]phthalazine derivatives against acute and chronic phases of Chagas disease.
Sánchez-Moreno M, Sanz AM, Gómez-Contreras F, Navarro P, Marín C, Ramírez-Macias I, Rosales MJ, Olmo F, Garcia-Aranda I, Campayo L, Cano C, Arrebola F, Yunta MJ. Sánchez-Moreno M, et al. Among authors: campayo l. J Med Chem. 2011 Feb 24;54(4):970-9. doi: 10.1021/jm101198k. Epub 2011 Jan 13. J Med Chem. 2011. PMID: 21229977
In vitro leishmanicidal activity of imidazole- or pyrazole-based benzo[g]phthalazine derivatives against Leishmania infantum and Leishmania braziliensis species.
Sánchez-Moreno M, Gómez-Contreras F, Navarro P, Marín C, Ramírez-Macías I, Olmo F, Sanz AM, Campayo L, Cano C, Yunta MJ. Sánchez-Moreno M, et al. Among authors: campayo l. J Antimicrob Chemother. 2012 Feb;67(2):387-97. doi: 10.1093/jac/dkr480. Epub 2011 Nov 29. J Antimicrob Chemother. 2012. PMID: 22127582
Imidazole-containing phthalazine derivatives inhibit Fe-SOD performance in Leishmania species and are active in vitro against visceral and mucosal leishmaniasis.
Sánchez-Moreno M, Gómez-Contreras F, Navarro P, Marín C, Ramírez-Macías I, Rosales MJ, Campayo L, Cano C, Sanz AM, Yunta MJ. Sánchez-Moreno M, et al. Among authors: campayo l. Parasitology. 2015 Jul;142(8):1115-29. doi: 10.1017/S0031182015000219. Epub 2015 Mar 31. Parasitology. 2015. PMID: 25823476
1,4-Bis(alkylamino)benzo[g]phthalazines able to form dinuclear complexes of Cu(II) which as free ligands behave as SOD inhibitors and show efficient in vitro activity against Trypanosoma cruzi.
Rodríguez-Ciria M, Sanz AM, Yunta MJ, Gómez-Contreras F, Navarro P, Sánchez-Moreno M, Boutaleb-Charki S, Osuna A, Castiñeiras A, Pardo M, Cano C, Campayo L. Rodríguez-Ciria M, et al. Among authors: campayo l. Bioorg Med Chem. 2007 Mar 1;15(5):2081-91. doi: 10.1016/j.bmc.2006.12.033. Epub 2006 Dec 23. Bioorg Med Chem. 2007. PMID: 17222558
Synthesis and cytotoxic activity of a new potential DNA bisintercalator: 1,4-Bis{3-[N-(4-chlorobenzo[g]phthalazin-1-yl)aminopropyl]}piperazine.
Galisteo J, Navarro P, Campayo L, Yunta MJ, Gómez-Contreras F, Villa-Pulgarin JA, Sierra BG, Mollinedo F, Gonzalez J, Garcia-España E. Galisteo J, et al. Among authors: campayo l. Bioorg Med Chem. 2010 Jul 15;18(14):5301-9. doi: 10.1016/j.bmc.2010.05.053. Epub 2010 May 24. Bioorg Med Chem. 2010. PMID: 20538470
Imidazole-containing phthalazine derivatives inhibit Fe-SOD performance in Leishmania species and are active in vitro against visceral and mucosal leishmaniasis--CORRIGENDUM.
Sánchez-Moreno M, Gómez-Contreras F, Navarro P, Marín C, Ramírez-Macías I, Rosales MJ, Campayo L, Cano C, Sanz AM, Yunta MJ. Sánchez-Moreno M, et al. Among authors: campayo l. Parasitology. 2015 Sep;142(10):1350. doi: 10.1017/S0031182015000657. Epub 2015 Jun 9. Parasitology. 2015. PMID: 26054948 No abstract available.
16 results