Cameron MD - Search Results

1

DNA-Encoded Library Screening To Inform Design of a Ribonuclease Targeting Chimera (RiboTAC).

Meyer SM, Tanaka T, Zanon PRA, Baisden JT, Abegg D, Yang X, Akahori Y, Alshakarchi Z, Cameron MD, Adibekian A, Disney MD. Meyer SM, et al. Among authors: cameron md. J Am Chem Soc. 2022 Nov 23;144(46):21096-21102. doi: 10.1021/jacs.2c07217. Epub 2022 Nov 7. J Am Chem Soc. 2022. PMID: 36342850 Free PMC article.

2

Design of a small molecule against an oncogenic noncoding RNA.

Velagapudi SP, Cameron MD, Haga CL, Rosenberg LH, Lafitte M, Duckett DR, Phinney DG, Disney MD. Velagapudi SP, et al. Among authors: cameron md. Proc Natl Acad Sci U S A. 2016 May 24;113(21):5898-903. doi: 10.1073/pnas.1523975113. Epub 2016 May 11. Proc Natl Acad Sci U S A. 2016. PMID: 27170187 Free PMC article.

3

Precise small-molecule recognition of a toxic CUG RNA repeat expansion.

Rzuczek SG, Colgan LA, Nakai Y, Cameron MD, Furling D, Yasuda R, Disney MD. Rzuczek SG, et al. Among authors: cameron md. Nat Chem Biol. 2017 Feb;13(2):188-193. doi: 10.1038/nchembio.2251. Epub 2016 Dec 12. Nat Chem Biol. 2017. PMID: 27941760 Free PMC article.

4

Precise small-molecule cleavage of an r(CUG) repeat expansion in a myotonic dystrophy mouse model.

Angelbello AJ, Rzuczek SG, Mckee KK, Chen JL, Olafson H, Cameron MD, Moss WN, Wang ET, Disney MD. Angelbello AJ, et al. Among authors: cameron md. Proc Natl Acad Sci U S A. 2019 Apr 16;116(16):7799-7804. doi: 10.1073/pnas.1901484116. Epub 2019 Mar 29. Proc Natl Acad Sci U S A. 2019. PMID: 30926669 Free PMC article.

5

Design of a small molecule that stimulates vascular endothelial growth factor A enabled by screening RNA fold-small molecule interactions.

Haniff HS, Knerr L, Liu X, Crynen G, Boström J, Abegg D, Adibekian A, Lekah E, Wang KW, Cameron MD, Yildirim I, Lemurell M, Disney MD. Haniff HS, et al. Among authors: cameron md. Nat Chem. 2020 Oct;12(10):952-961. doi: 10.1038/s41557-020-0514-4. Epub 2020 Aug 24. Nat Chem. 2020. PMID: 32839603 Free PMC article.

6

Small molecule 1a reduces FMRpolyG-mediated toxicity in in vitro and in vivo models for FMR1 premutation.

Haify SN, Buijsen RAM, Verwegen L, Severijnen LWFM, de Boer H, Boumeester V, Monshouwer R, Yang WY, Cameron MD, Willemsen R, Disney MD, Hukema RK. Haify SN, et al. Among authors: cameron md. Hum Mol Genet. 2021 Aug 12;30(17):1632-1648. doi: 10.1093/hmg/ddab143. Hum Mol Genet. 2021. PMID: 34077515 Free PMC article.

7

Reprogramming of Protein-Targeted Small-Molecule Medicines to RNA by Ribonuclease Recruitment.

Zhang P, Liu X, Abegg D, Tanaka T, Tong Y, Benhamou RI, Baisden J, Crynen G, Meyer SM, Cameron MD, Chatterjee AK, Adibekian A, Childs-Disney JL, Disney MD. Zhang P, et al. Among authors: cameron md. J Am Chem Soc. 2021 Aug 25;143(33):13044-13055. doi: 10.1021/jacs.1c02248. Epub 2021 Aug 13. J Am Chem Soc. 2021. PMID: 34387474 Free PMC article.

8

Dual Inhibitors of Main Protease (M^Pro) and Cathepsin L as Potent Antivirals against SARS-CoV2.

Mondal S, Chen Y, Lockbaum GJ, Sen S, Chaudhuri S, Reyes AC, Lee JM, Kaur AN, Sultana N, Cameron MD, Shaffer SA, Schiffer CA, Fitzgerald KA, Thompson PR. Mondal S, et al. Among authors: cameron md. J Am Chem Soc. 2022 Nov 23;144(46):21035-21045. doi: 10.1021/jacs.2c04626. Epub 2022 Nov 10. J Am Chem Soc. 2022. PMID: 36356199 Free PMC article.

9

Development of LB244, an Irreversible STING Antagonist.

Barasa L, Chaudhuri S, Zhou JY, Jiang Z, Choudhary S, Green RM, Wiggin E, Cameron M, Humphries F, Fitzgerald KA, Thompson PR. Barasa L, et al. J Am Chem Soc. 2023 Sep 20;145(37):20273-20288. doi: 10.1021/jacs.3c03637. Epub 2023 Sep 11. J Am Chem Soc. 2023. PMID: 37695732

10

Development of dual casein kinase 1δ/1ε (CK1δ/ε) inhibitors for treatment of breast cancer.

Monastyrskyi A, Nilchan N, Quereda V, Noguchi Y, Ruiz C, Grant W, Cameron M, Duckett D, Roush W. Monastyrskyi A, et al. Bioorg Med Chem. 2018 Feb 1;26(3):590-602. doi: 10.1016/j.bmc.2017.12.020. Epub 2017 Dec 15. Bioorg Med Chem. 2018. PMID: 29289448 Free PMC article.

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