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Reprogramming of Protein-Targeted Small-Molecule Medicines to RNA by Ribonuclease Recruitment.
Zhang P, Liu X, Abegg D, Tanaka T, Tong Y, Benhamou RI, Baisden J, Crynen G, Meyer SM, Cameron MD, Chatterjee AK, Adibekian A, Childs-Disney JL, Disney MD. Zhang P, et al. Among authors: cameron md. J Am Chem Soc. 2021 Aug 25;143(33):13044-13055. doi: 10.1021/jacs.1c02248. Epub 2021 Aug 13. J Am Chem Soc. 2021. PMID: 34387474 Free PMC article.
Small molecule amides as potent ROR-γ selective modulators.
Khan PM, El-Gendy Bel-D, Kumar N, Garcia-Ordonez R, Lin L, Ruiz CH, Cameron MD, Griffin PR, Kamenecka TM. Khan PM, et al. Among authors: cameron md. Bioorg Med Chem Lett. 2013 Jan 15;23(2):532-6. doi: 10.1016/j.bmcl.2012.11.025. Epub 2012 Nov 22. Bioorg Med Chem Lett. 2013. PMID: 23232056 Free PMC article.
Design of a small molecule against an oncogenic noncoding RNA.
Velagapudi SP, Cameron MD, Haga CL, Rosenberg LH, Lafitte M, Duckett DR, Phinney DG, Disney MD. Velagapudi SP, et al. Among authors: cameron md. Proc Natl Acad Sci U S A. 2016 May 24;113(21):5898-903. doi: 10.1073/pnas.1523975113. Epub 2016 May 11. Proc Natl Acad Sci U S A. 2016. PMID: 27170187 Free PMC article.
Precise small-molecule recognition of a toxic CUG RNA repeat expansion.
Rzuczek SG, Colgan LA, Nakai Y, Cameron MD, Furling D, Yasuda R, Disney MD. Rzuczek SG, et al. Among authors: cameron md. Nat Chem Biol. 2017 Feb;13(2):188-193. doi: 10.1038/nchembio.2251. Epub 2016 Dec 12. Nat Chem Biol. 2017. PMID: 27941760 Free PMC article.
Discovery of small-molecule enzyme activators by activity-based protein profiling.
Kok BP, Ghimire S, Kim W, Chatterjee S, Johns T, Kitamura S, Eberhardt J, Ogasawara D, Xu J, Sukiasyan A, Kim SM, Godio C, Bittencourt JM, Cameron M, Galmozzi A, Forli S, Wolan DW, Cravatt BF, Boger DL, Saez E. Kok BP, et al. Nat Chem Biol. 2020 Sep;16(9):997-1005. doi: 10.1038/s41589-020-0555-4. Epub 2020 Jun 8. Nat Chem Biol. 2020. PMID: 32514184 Free PMC article.
Dual Inhibitors of Main Protease (MPro) and Cathepsin L as Potent Antivirals against SARS-CoV2.
Mondal S, Chen Y, Lockbaum GJ, Sen S, Chaudhuri S, Reyes AC, Lee JM, Kaur AN, Sultana N, Cameron MD, Shaffer SA, Schiffer CA, Fitzgerald KA, Thompson PR. Mondal S, et al. Among authors: cameron md. J Am Chem Soc. 2022 Nov 23;144(46):21035-21045. doi: 10.1021/jacs.2c04626. Epub 2022 Nov 10. J Am Chem Soc. 2022. PMID: 36356199 Free PMC article.
165 results