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Deficient Endoplasmic Reticulum-Mitochondrial Phosphatidylserine Transfer Causes Liver Disease.
Hernández-Alvarez MI, Sebastián D, Vives S, Ivanova S, Bartoccioni P, Kakimoto P, Plana N, Veiga SR, Hernández V, Vasconcelos N, Peddinti G, Adrover A, Jové M, Pamplona R, Gordaliza-Alaguero I, Calvo E, Cabré N, Castro R, Kuzmanic A, Boutant M, Sala D, Hyotylainen T, Orešič M, Fort J, Errasti-Murugarren E, Rodrígues CMP, Orozco M, Joven J, Cantó C, Palacin M, Fernández-Veledo S, Vendrell J, Zorzano A. Hernández-Alvarez MI, et al. Among authors: calvo e. Cell. 2019 May 2;177(4):881-895.e17. doi: 10.1016/j.cell.2019.04.010. Cell. 2019. PMID: 31051106 Free article.
Survivin, a key player in cancer progression, increases in obesity and protects adipose tissue stem cells from apoptosis.
Ejarque M, Ceperuelo-Mallafré V, Serena C, Pachón G, Núñez-Álvarez Y, Terrón-Puig M, Calvo E, Núñez-Roa C, Oliva-Olivera W, Tinahones FJ, Peinado MA, Vendrell J, Fernández-Veledo S. Ejarque M, et al. Among authors: calvo e. Cell Death Dis. 2017 May 18;8(5):e2802. doi: 10.1038/cddis.2017.209. Cell Death Dis. 2017. PMID: 28518147 Free PMC article.
SUCNR1 controls an anti-inflammatory program in macrophages to regulate the metabolic response to obesity.
Keiran N, Ceperuelo-Mallafré V, Calvo E, Hernández-Alvarez MI, Ejarque M, Núñez-Roa C, Horrillo D, Maymó-Masip E, Rodríguez MM, Fradera R, de la Rosa JV, Jorba R, Megia A, Zorzano A, Medina-Gómez G, Serena C, Castrillo A, Vendrell J, Fernández-Veledo S. Keiran N, et al. Among authors: calvo e. Nat Immunol. 2019 May;20(5):581-592. doi: 10.1038/s41590-019-0372-7. Epub 2019 Apr 8. Nat Immunol. 2019. PMID: 30962591 Free article.
Adipose tissue is a key organ for the beneficial effects of GLP-2 metabolic function.
Ejarque M, Sabadell-Basallote J, Beiroa D, Calvo E, Keiran N, Nuñez-Roa C, Rodríguez MDM, Sabench F, Del Castillo D, Jimenez V, Bosch F, Nogueiras R, Vendrell J, Fernández-Veledo S. Ejarque M, et al. Among authors: calvo e. Br J Pharmacol. 2021 May;178(10):2131-2145. doi: 10.1111/bph.15278. Epub 2020 Nov 19. Br J Pharmacol. 2021. PMID: 32986861 Free article.
Effects of stem cells from inducible brown adipose tissue on diet-induced obesity in mice.
Calvo E, Keiran N, Núñez-Roa C, Maymó-Masip E, Ejarque M, Sabadell-Basallote J, Del Mar Rodríguez-Peña M, Ceperuelo-Mallafré V, Seco J, Benaiges E, Michalopoulou T, Jorba R, Vendrell J, Fernández-Veledo S. Calvo E, et al. Sci Rep. 2021 Jul 6;11(1):13923. doi: 10.1038/s41598-021-93224-6. Sci Rep. 2021. PMID: 34230537 Free PMC article.
Orally administered Odoribacter laneus improves glucose control and inflammatory profile in obese mice by depleting circulating succinate.
Huber-Ruano I, Calvo E, Mayneris-Perxachs J, Rodríguez-Peña MM, Ceperuelo-Mallafré V, Cedó L, Núñez-Roa C, Miro-Blanch J, Arnoriaga-Rodríguez M, Balvay A, Maudet C, García-Roves P, Yanes O, Rabot S, Grimaud GM, De Prisco A, Amoruso A, Fernández-Real JM, Vendrell J, Fernández-Veledo S. Huber-Ruano I, et al. Among authors: calvo e. Microbiome. 2022 Aug 25;10(1):135. doi: 10.1186/s40168-022-01306-y. Microbiome. 2022. PMID: 36002880 Free PMC article.
Protective effects of the succinate/SUCNR1 axis on damaged hepatocytes in NAFLD.
Marsal-Beltran A, Rodríguez-Castellano A, Astiarraga B, Calvo E, Rada P, Madeira A, Rodríguez-Peña MM, Llauradó G, Núñez-Roa C, Gómez-Santos B, Maymó-Masip E, Bosch R, Frutos MD, Moreno-Navarrete JM, Ramos-Molina B, Aspichueta P, Joven J, Fernández-Real JM, Quer JC, Valverde ÁM, Pardo A, Vendrell J, Ceperuelo-Mallafré V, Fernández-Veledo S. Marsal-Beltran A, et al. Among authors: calvo e. Metabolism. 2023 Aug;145:155630. doi: 10.1016/j.metabol.2023.155630. Epub 2023 Jun 13. Metabolism. 2023. PMID: 37315889 Free article.
1,088 results