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NFκB and NLRP3/NLRC4 inflammasomes regulate differentiation, activation and functional properties of monocytes in response to distinct SARS-CoV-2 proteins.
Tsukalov I, Sánchez-Cerrillo I, Rajas O, Avalos E, Iturricastillo G, Esparcia L, Buzón MJ, Genescà M, Scagnetti C, Popova O, Martin-Cófreces N, Calvet-Mirabent M, Marcos-Jimenez A, Martínez-Fleta P, Delgado-Arévalo C, de Los Santos I, Muñoz-Calleja C, Calzada MJ, González Álvaro I, Palacios-Calvo J, Alfranca A, Ancochea J, Sánchez-Madrid F, Martin-Gayo E. Tsukalov I, et al. Among authors: calvet mirabent m. Nat Commun. 2024 Mar 7;15(1):2100. doi: 10.1038/s41467-024-46322-8. Nat Commun. 2024. PMID: 38453949 Free PMC article.
MICa/b-dependent activation of natural killer cells by CD64+ inflammatory type 2 dendritic cells contributes to autoimmunity.
Sánchez-Cerrillo I, Calzada-Fraile D, Triguero-Martínez A, Calvet-Mirabent M, Popova O, Delgado-Arévalo C, Valdivia-Mazeyra M, Ramírez-Huesca M, de Luis EV, Benguría A, Aceña-Gonzalo T, Moreno-Vellisca R, de Llano MA, de la Fuente H, Tsukalov I, Delgado-Wicke P, Fernández-Ruiz E, Roy-Vallejo E, Tejedor-Lázaro R, Ramiro A, Iborra S, Sánchez-Madrid F, Dopazo A, Álvaro IG, Castañeda S, Martin-Gayo E. Sánchez-Cerrillo I, et al. Among authors: calvet mirabent m. EMBO J. 2023 Dec 1;42(23):e113714. doi: 10.15252/embj.2023113714. Epub 2023 Nov 2. EMBO J. 2023. PMID: 37916875 Free PMC article.
KLRG1 expression on natural killer cells is associated with HIV persistence, and its targeting promotes the reduction of the viral reservoir.
Astorga-Gamaza A, Perea D, Sanchez-Gaona N, Calvet-Mirabent M, Gallego-Cortés A, Grau-Expósito J, Sanchez-Cerrillo I, Rey J, Castellví J, Curran A, Burgos J, Navarro J, Suanzes P, Falcó V, Genescà M, Martín-Gayo E, Buzon MJ. Astorga-Gamaza A, et al. Among authors: calvet mirabent m. Cell Rep Med. 2023 Oct 17;4(10):101202. doi: 10.1016/j.xcrm.2023.101202. Epub 2023 Sep 22. Cell Rep Med. 2023. PMID: 37741278 Free PMC article.
NLRC4-mediated activation of CD1c+ DC contributes to perpetuation of synovitis in rheumatoid arthritis.
Delgado-Arévalo C, Calvet-Mirabent M, Triguero-Martínez A, Vázquez de Luis E, Benguría-Filippini A, Largo R, Calzada-Fraile D, Popova O, Sánchez-Cerrillo I, Tsukalov I, Moreno-Vellisca R, de la Fuente H, Herrero-Beaumont G, Ramiro A, Sánchez-Madrid F, Castañeda S, Dopazo A, González Álvaro I, Martin-Gayo E. Delgado-Arévalo C, et al. Among authors: calvet mirabent m. JCI Insight. 2022 Nov 22;7(22):e152886. doi: 10.1172/jci.insight.152886. JCI Insight. 2022. PMID: 36194479 Free PMC article.
Antiretroviral therapy duration and immunometabolic state determine efficacy of ex vivo dendritic cell-based treatment restoring functional HIV-specific CD8+ T cells in people living with HIV.
Calvet-Mirabent M, Sánchez-Cerrillo I, Martín-Cófreces N, Martínez-Fleta P, de la Fuente H, Tsukalov I, Delgado-Arévalo C, Calzada MJ, de Los Santos I, Sanz J, García-Fraile L, Sánchez-Madrid F, Alfranca A, Muñoz-Fernández MÁ, Buzón MJ, Martín-Gayo E. Calvet-Mirabent M, et al. EBioMedicine. 2022 Jul;81:104090. doi: 10.1016/j.ebiom.2022.104090. Epub 2022 Jun 2. EBioMedicine. 2022. PMID: 35665682 Free PMC article.
Poly I:C and STING agonist-primed DC increase lymphoid tissue polyfunctional HIV-1-specific CD8+ T cells and limit CD4+ T-cell loss in BLT mice.
Calvet-Mirabent M, Claiborne DT, Deruaz M, Tanno S, Serra C, Delgado-Arévalo C, Sánchez-Cerrillo I, de Los Santos I, Sanz J, García-Fraile L, Sánchez-Madrid F, Alfranca A, Muñoz-Fernández MÁ, Allen TM, Buzón MJ, Balazs A, Vrbanac V, Martín-Gayo E. Calvet-Mirabent M, et al. Eur J Immunol. 2022 Mar;52(3):447-461. doi: 10.1002/eji.202149502. Epub 2022 Jan 8. Eur J Immunol. 2022. PMID: 34935145 Free article.