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A genetically modified minipig model for Alzheimer's disease with SORL1 haploinsufficiency.
Andersen OM, Bøgh N, Landau AM, Pløen GG, Jensen AMG, Monti G, Ulhøi BP, Nyengaard JR, Jacobsen KR, Jørgensen MM, Holm IE, Kristensen ML, Alstrup AKO, Hansen ESS, Teunissen CE, Breidenbach L, Droescher M, Liu Y, Pedersen HS, Callesen H, Luo Y, Bolund L, Brooks DJ, Laustsen C, Small SA, Mikkelsen LF, Sørensen CB. Andersen OM, et al. Among authors: callesen h. Cell Rep Med. 2022 Sep 20;3(9):100740. doi: 10.1016/j.xcrm.2022.100740. Epub 2022 Sep 12. Cell Rep Med. 2022. PMID: 36099918 Free PMC article.
Pig transgenesis by Sleeping Beauty DNA transposition.
Jakobsen JE, Li J, Kragh PM, Moldt B, Lin L, Liu Y, Schmidt M, Winther KD, Schyth BD, Holm IE, Vajta G, Bolund L, Callesen H, Jørgensen AL, Nielsen AL, Mikkelsen JG. Jakobsen JE, et al. Among authors: callesen h. Transgenic Res. 2011 Jun;20(3):533-45. doi: 10.1007/s11248-010-9438-x. Epub 2010 Aug 29. Transgenic Res. 2011. PMID: 20803249
Development of transgenic cloned pig models of skin inflammation by DNA transposon-directed ectopic expression of human β1 and α2 integrin.
Staunstrup NH, Madsen J, Primo MN, Li J, Liu Y, Kragh PM, Li R, Schmidt M, Purup S, Dagnæs-Hansen F, Svensson L, Petersen TK, Callesen H, Bolund L, Mikkelsen JG. Staunstrup NH, et al. Among authors: callesen h. PLoS One. 2012;7(5):e36658. doi: 10.1371/journal.pone.0036658. Epub 2012 May 10. PLoS One. 2012. PMID: 22590584 Free PMC article.
Generation of minipigs with targeted transgene insertion by recombinase-mediated cassette exchange (RMCE) and somatic cell nuclear transfer (SCNT).
Jakobsen JE, Johansen MG, Schmidt M, Dagnæs-Hansen F, Dam K, Gunnarsson A, Liu Y, Kragh PM, Li R, Holm IE, Callesen H, Mikkelsen JG, Nielsen AL, Jørgensen AL. Jakobsen JE, et al. Among authors: callesen h. Transgenic Res. 2013 Aug;22(4):709-23. doi: 10.1007/s11248-012-9671-6. Epub 2012 Oct 31. Transgenic Res. 2013. PMID: 23111619 Free PMC article.
Familial hypercholesterolemia and atherosclerosis in cloned minipigs created by DNA transposition of a human PCSK9 gain-of-function mutant.
Al-Mashhadi RH, Sørensen CB, Kragh PM, Christoffersen C, Mortensen MB, Tolbod LP, Thim T, Du Y, Li J, Liu Y, Moldt B, Schmidt M, Vajta G, Larsen T, Purup S, Bolund L, Nielsen LB, Callesen H, Falk E, Mikkelsen JG, Bentzon JF. Al-Mashhadi RH, et al. Among authors: callesen h. Sci Transl Med. 2013 Jan 2;5(166):166ra1. doi: 10.1126/scitranslmed.3004853. Sci Transl Med. 2013. PMID: 23283366
170 results