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Transcriptional repressor REST drives lineage stage-specific chromatin compaction at Ptch1 and increases AKT activation in a mouse model of medulloblastoma.
Dobson THW, Tao RH, Swaminathan J, Maegawa S, Shaik S, Bravo-Alegria J, Sharma A, Kennis B, Yang Y, Callegari K, Haltom AR, Taylor P, Kogiso M, Qi L, Khatua S, Goldman S, Lulla RR, Fangusaro J, MacDonald TJ, Li XN, Hawkins C, Rajaram V, Gopalakrishnan V. Dobson THW, et al. Among authors: callegari k. Sci Signal. 2019 Jan 22;12(565):eaan8680. doi: 10.1126/scisignal.aan8680. Sci Signal. 2019. PMID: 30670636 Free PMC article.
REST upregulates gremlin to modulate diffuse intrinsic pontine glioma vasculature.
Shaik S, Kennis B, Maegawa S, Schadler K, Yanwen Y, Callegari K, Lulla RR, Goldman S, Nazarian J, Rajaram V, Fangusaro J, Gopalakrishnan V. Shaik S, et al. Among authors: callegari k. Oncotarget. 2017 Dec 28;9(4):5233-5250. doi: 10.18632/oncotarget.23750. eCollection 2018 Jan 12. Oncotarget. 2017. PMID: 29435175 Free PMC article.
Prion-like features of misfolded Aβ and tau aggregates.
Morales R, Callegari K, Soto C. Morales R, et al. Among authors: callegari k. Virus Res. 2015 Sep 2;207:106-12. doi: 10.1016/j.virusres.2014.12.031. Epub 2015 Jan 6. Virus Res. 2015. PMID: 25575736 Review.