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Complementary cell-based high-throughput screens identify novel modulators of the unfolded protein response.
Fribley AM, Cruz PG, Miller JR, Callaghan MU, Cai P, Narula N, Neubig RR, Showalter HD, Larsen SD, Kirchhoff PD, Larsen MJ, Burr DA, Schultz PJ, Jacobs RR, Tamayo-Castillo G, Ron D, Sherman DH, Kaufman RJ. Fribley AM, et al. Among authors: callaghan mu. J Biomol Screen. 2011 Sep;16(8):825-35. doi: 10.1177/1087057111414893. Epub 2011 Aug 15. J Biomol Screen. 2011. PMID: 21844328 Free PMC article.
Cantharidins induce ER stress and a terminal unfolded protein response in OSCC.
Xi Y, Garshott DM, Brownell AL, Yoo GH, Lin HS, Freeburg TL, Yoo NG, Kaufman RJ, Callaghan MU, Fribley AM. Xi Y, et al. Among authors: callaghan mu. J Dent Res. 2015 Feb;94(2):320-9. doi: 10.1177/0022034514559376. Epub 2014 Nov 25. J Dent Res. 2015. PMID: 25425581 Free PMC article.
Borrelidin Induces the Unfolded Protein Response in Oral Cancer Cells and Chop-Dependent Apoptosis.
Sidhu A, Miller JR, Tripathi A, Garshott DM, Brownell AL, Chiego DJ, Arevang C, Zeng Q, Jackson LC, Bechler SA, Callaghan MU, Yoo GH, Sethi S, Lin HS, Callaghan JH, Tamayo-Castillo G, Sherman DH, Kaufman RJ, Fribley AM. Sidhu A, et al. Among authors: callaghan jh, callaghan mu. ACS Med Chem Lett. 2015 Sep 8;6(11):1122-7. doi: 10.1021/acsmedchemlett.5b00133. eCollection 2015 Nov 12. ACS Med Chem Lett. 2015. PMID: 26617965 Free PMC article.
Targeting the unfolded protein response in head and neck and oral cavity cancers.
Cole DW, Svider PF, Shenouda KG, Lee PB, Yoo NG, McLeod TM, Mutchnick SA, Yoo GH, Kaufman RJ, Callaghan MU, Fribley AM. Cole DW, et al. Among authors: callaghan mu. Exp Cell Res. 2019 Sep 1;382(1):111386. doi: 10.1016/j.yexcr.2019.04.007. Epub 2019 May 7. Exp Cell Res. 2019. PMID: 31075256 Free PMC article. Review.
Large-scale analysis of UPR-mediated apoptosis in human cells.
Fribley AM, Miller JR, Reist TE, Callaghan MU, Kaufman RJ. Fribley AM, et al. Among authors: callaghan mu. Methods Enzymol. 2011;491:57-71. doi: 10.1016/B978-0-12-385928-0.00004-3. Methods Enzymol. 2011. PMID: 21329794 Free PMC article.
Discovery of Sulfonamidebenzamides as Selective Apoptotic CHOP Pathway Activators of the Unfolded Protein Response.
Flaherty DP, Miller JR, Garshott DM, Hedrick M, Gosalia P, Li Y, Milewski M, Sugarman E, Vasile S, Salaniwal S, Su Y, Smith LH, Chung TD, Pinkerton AB, Aubé J, Callaghan MU, Golden JE, Fribley AM, Kaufman RJ. Flaherty DP, et al. Among authors: callaghan mu. ACS Med Chem Lett. 2014 Oct 29;5(12):1278-1283. doi: 10.1021/ml5003234. eCollection 2014 Dec 11. ACS Med Chem Lett. 2014. PMID: 25530830 Free PMC article.
76 results