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Extracellular truncated tau causes early presynaptic dysfunction associated with Alzheimer's disease and other tauopathies.
Florenzano F, Veronica C, Ciasca G, Ciotti MT, Pittaluga A, Olivero G, Feligioni M, Iannuzzi F, Latina V, Maria Sciacca MF, Sinopoli A, Milardi D, Pappalardo G, Marco S, Papi M, Atlante A, Bobba A, Borreca A, Calissano P, Amadoro G. Florenzano F, et al. Among authors: calissano p. Oncotarget. 2017 Apr 22;8(39):64745-64778. doi: 10.18632/oncotarget.17371. eCollection 2017 Sep 12. Oncotarget. 2017. PMID: 29029390 Free PMC article.
Dynamic structural determinants underlie the neurotoxicity of the N-terminal tau 26-44 peptide in Alzheimer's disease and other human tauopathies.
Perini G, Ciasca G, Minelli E, Papi M, Palmieri V, Maulucci G, Nardini M, Latina V, Corsetti V, Florenzano F, Calissano P, De Spirito M, Amadoro G. Perini G, et al. Among authors: calissano p. Int J Biol Macromol. 2019 Dec 1;141:278-289. doi: 10.1016/j.ijbiomac.2019.08.220. Epub 2019 Aug 27. Int J Biol Macromol. 2019. PMID: 31470053
Systemic delivery of a specific antibody targeting the pathological N-terminal truncated tau peptide reduces retinal degeneration in a mouse model of Alzheimer's Disease.
Latina V, Giacovazzo G, Cordella F, Balzamino BO, Micera A, Varano M, Marchetti C, Malerba F, Florio R, Ercole BB, La Regina F, Atlante A, Coccurello R, Di Angelantonio S, Calissano P, Amadoro G. Latina V, et al. Among authors: calissano p. Acta Neuropathol Commun. 2021 Mar 9;9(1):38. doi: 10.1186/s40478-021-01138-1. Acta Neuropathol Commun. 2021. PMID: 33750467 Free PMC article.
NH2-truncated human tau induces deregulated mitophagy in neurons by aberrant recruitment of Parkin and UCHL-1: implications in Alzheimer's disease.
Corsetti V, Florenzano F, Atlante A, Bobba A, Ciotti MT, Natale F, Della Valle F, Borreca A, Manca A, Meli G, Ferraina C, Feligioni M, D'Aguanno S, Bussani R, Ammassari-Teule M, Nicolin V, Calissano P, Amadoro G. Corsetti V, et al. Among authors: calissano p. Hum Mol Genet. 2015 Jun 1;24(11):3058-81. doi: 10.1093/hmg/ddv059. Epub 2015 Feb 15. Hum Mol Genet. 2015. PMID: 25687137 Free article.
Passive immunotherapy for N-truncated tau ameliorates the cognitive deficits in two mouse Alzheimer's disease models.
Corsetti V, Borreca A, Latina V, Giacovazzo G, Pignataro A, Krashia P, Natale F, Cocco S, Rinaudo M, Malerba F, Florio R, Ciarapica R, Coccurello R, D'Amelio M, Ammassari-Teule M, Grassi C, Calissano P, Amadoro G. Corsetti V, et al. Among authors: calissano p. Brain Commun. 2020 Apr 6;2(1):fcaa039. doi: 10.1093/braincomms/fcaa039. eCollection 2020. Brain Commun. 2020. PMID: 32954296 Free PMC article.
184 results