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Page 1
Elucidation and Pharmacologic Targeting of Master Regulator Dependencies in Coexisting Diffuse Midline Glioma Subpopulations.
Fernández EC, Tomassoni L, Zhang X, Wang J, Obradovic A, Laise P, Griffin AT, Vlahos L, Minns HE, Morales DV, Simmons C, Gallitto M, Wei HJ, Martins TJ, Becker PS, Crawford JR, Tzaridis T, Wechsler-Reya RJ, Garvin J, Gartrell RD, Szalontay L, Zacharoulis S, Wu CC, Zhang Z, Califano A, Pavisic J. Fernández EC, et al. Among authors: califano a. bioRxiv [Preprint]. 2024 Mar 17:2024.03.17.585370. doi: 10.1101/2024.03.17.585370. bioRxiv. 2024. PMID: 38559080 Free PMC article. Preprint.
Ras-dependent activation of BMAL2 regulates hypoxic metabolism in pancreatic cancer.
Maurer HC, Curiel-Garcia A, Holmstrom S, Laise P, Palermo CF, Sastra SA, Andren A, Li Z, LeLarge T, Sagalovskiy I, Ross DR, Rosario V, Lu K, Ferraiuolo E, Spinosa N, Wong W, Shaw K, Chabot JA, Genkinger J, Hibshoosh H, Manji GA, Iuga A, Schmid RM, Badgley MA, Johnson K, Califano A, Lyssiotis C, Olive KP. Maurer HC, et al. Among authors: califano a. bioRxiv [Preprint]. 2023 Mar 21:2023.03.19.533333. doi: 10.1101/2023.03.19.533333. bioRxiv. 2023. PMID: 36993718 Free PMC article. Preprint.
Single-Cell Genomics Reveals a Novel Cell State During Smooth Muscle Cell Phenotypic Switching and Potential Therapeutic Targets for Atherosclerosis in Mouse and Human.
Pan H, Xue C, Auerbach BJ, Fan J, Bashore AC, Cui J, Yang DY, Trignano SB, Liu W, Shi J, Ihuegbu CO, Bush EC, Worley J, Vlahos L, Laise P, Solomon RA, Connolly ES, Califano A, Sims PA, Zhang H, Li M, Reilly MP. Pan H, et al. Among authors: califano a. Circulation. 2020 Nov 24;142(21):2060-2075. doi: 10.1161/CIRCULATIONAHA.120.048378. Epub 2020 Sep 23. Circulation. 2020. PMID: 32962412 Free PMC article.
Single-cell protein activity analysis identifies recurrence-associated renal tumor macrophages.
Obradovic A, Chowdhury N, Haake SM, Ager C, Wang V, Vlahos L, Guo XV, Aggen DH, Rathmell WK, Jonasch E, Johnson JE, Roth M, Beckermann KE, Rini BI, McKiernan J, Califano A, Drake CG. Obradovic A, et al. Among authors: califano a. Cell. 2021 May 27;184(11):2988-3005.e16. doi: 10.1016/j.cell.2021.04.038. Epub 2021 May 20. Cell. 2021. PMID: 34019793 Free PMC article.
A Model for Network-Based Identification and Pharmacological Targeting of Aberrant, Replication-Permissive Transcriptional Programs Induced by Viral Infection.
Laise P, Stanifer ML, Bosker G, Sun X, Triana S, Doldan P, La Manna F, De Menna M, Realubit RB, Pampou S, Karan C, Alexandrov T, Kruithof-de Julio M, Califano A, Boulant S, Alvarez MJ. Laise P, et al. Among authors: califano a. Res Sq [Preprint]. 2022 Feb 4:rs.3.rs-1287631. doi: 10.21203/rs.3.rs-1287631/v1. Res Sq. 2022. PMID: 35132404 Free PMC article. Updated. Preprint.
344 results