Caldecott KW - Search Results

1

Unrepaired base excision repair intermediates in template DNA strands trigger replication fork collapse and PARP inhibitor sensitivity.

Serrano-Benitez A, Wells SE, Drummond-Clarke L, Russo LC, Thomas JC, Leal GA, Farrow M, Edgerton JM, Balasubramanian S, Yang M, Frezza C, Gautam A, Brazina J, Burdova K, Hoch NC, Jackson SP, Caldecott KW. Serrano-Benitez A, et al. Among authors: caldecott kw. EMBO J. 2023 Sep 18;42(18):e113190. doi: 10.15252/embj.2022113190. Epub 2023 Jul 26. EMBO J. 2023. PMID: 37492888 Free PMC article.

2

Mutations in PNKP cause microcephaly, seizures and defects in DNA repair.

Shen J, Gilmore EC, Marshall CA, Haddadin M, Reynolds JJ, Eyaid W, Bodell A, Barry B, Gleason D, Allen K, Ganesh VS, Chang BS, Grix A, Hill RS, Topcu M, Caldecott KW, Barkovich AJ, Walsh CA. Shen J, et al. Among authors: caldecott kw. Nat Genet. 2010 Mar;42(3):245-9. doi: 10.1038/ng.526. Epub 2010 Jan 31. Nat Genet. 2010. PMID: 20118933 Free PMC article.

3

Spatial and temporal cellular responses to single-strand breaks in human cells.

Okano S, Lan L, Caldecott KW, Mori T, Yasui A. Okano S, et al. Among authors: caldecott kw. Mol Cell Biol. 2003 Jun;23(11):3974-81. doi: 10.1128/MCB.23.11.3974-3981.2003. Mol Cell Biol. 2003. PMID: 12748298 Free PMC article.

4

Mammalian DNA single-strand break repair: an X-ra(y)ted affair.

Caldecott KW. Caldecott KW. Bioessays. 2001 May;23(5):447-55. doi: 10.1002/bies.1063. Bioessays. 2001. PMID: 11340626 Review.

5

Biophysical characterization of human XRCC1 and its binding to damaged and undamaged DNA.

Mani RS, Karimi-Busheri F, Fanta M, Caldecott KW, Cass CE, Weinfeld M. Mani RS, et al. Among authors: caldecott kw. Biochemistry. 2004 Dec 28;43(51):16505-14. doi: 10.1021/bi048615m. Biochemistry. 2004. PMID: 15610045

6

Involvement of XRCC1 and DNA ligase III gene products in DNA base excision repair.

Cappelli E, Taylor R, Cevasco M, Abbondandolo A, Caldecott K, Frosina G. Cappelli E, et al. J Biol Chem. 1997 Sep 19;272(38):23970-5. doi: 10.1074/jbc.272.38.23970. J Biol Chem. 1997. PMID: 9295348 Free article.

7

Sensitivity of Chinese hamster ovary mutants defective in DNA double strand break repair to topoisomerase II inhibitors.

Jeggo PA, Caldecott K, Pidsley S, Banks GR. Jeggo PA, et al. Cancer Res. 1989 Dec 15;49(24 Pt 1):7057-63. Cancer Res. 1989. PMID: 2479475

8

Characterization of the XRCC1-DNA ligase III complex in vitro and its absence from mutant hamster cells.

Caldecott KW, Tucker JD, Stanker LH, Thompson LH. Caldecott KW, et al. Nucleic Acids Res. 1995 Dec 11;23(23):4836-43. doi: 10.1093/nar/23.23.4836. Nucleic Acids Res. 1995. PMID: 8532526 Free PMC article.

9

Central role for the XRCC1 BRCT I domain in mammalian DNA single-strand break repair.

Taylor RM, Thistlethwaite A, Caldecott KW. Taylor RM, et al. Among authors: caldecott kw. Mol Cell Biol. 2002 Apr;22(8):2556-63. doi: 10.1128/MCB.22.8.2556-2563.2002. Mol Cell Biol. 2002. PMID: 11909950 Free PMC article.

10

XRCC1 polypeptide interacts with DNA polymerase beta and possibly poly (ADP-ribose) polymerase, and DNA ligase III is a novel molecular 'nick-sensor' in vitro.

Caldecott KW, Aoufouchi S, Johnson P, Shall S. Caldecott KW, et al. Nucleic Acids Res. 1996 Nov 15;24(22):4387-94. doi: 10.1093/nar/24.22.4387. Nucleic Acids Res. 1996. PMID: 8948628 Free PMC article.

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