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A New Class of Bi- and Trifunctional Sugar Oximes as Antidotes against Organophosphorus Poisoning.
Da Silva O, Probst N, Landry C, Hanak AS, Warnault P, Coisne C, Calas AG, Gosselet F, Courageux C, Gastellier AJ, Trancart M, Baati R, Dehouck MP, Jean L, Nachon F, Renard PY, Dias J. Da Silva O, et al. Among authors: calas ag. J Med Chem. 2022 Mar 24;65(6):4649-4666. doi: 10.1021/acs.jmedchem.1c01748. Epub 2022 Mar 7. J Med Chem. 2022. PMID: 35255209 Free PMC article.
An easy method for the determination of active concentrations of cholinesterase reactivators in blood samples: Application to the efficacy assessment of non quaternary reactivators compared to HI-6 and pralidoxime in VX-poisoned mice.
Calas AG, Dias J, Rousseau C, Arboléas M, Touvrey-Loiodice M, Mercey G, Jean L, Renard PY, Nachon F. Calas AG, et al. Chem Biol Interact. 2017 Apr 1;267:11-16. doi: 10.1016/j.cbi.2016.03.009. Epub 2016 Mar 10. Chem Biol Interact. 2017. PMID: 26972668
Efficacy Assessment of an Uncharged Reactivator of NOP-Inhibited Acetylcholinesterase Based on Tetrahydroacridine Pyridine-Aldoxime Hybrid in Mouse Compared to Pralidoxime.
Calas AG, Hanak AS, Jaffré N, Nervo A, Dias J, Rousseau C, Courageux C, Brazzolotto X, Villa P, Obrecht A, Goossens JF, Landry C, Hachani J, Gosselet F, Dehouck MP, Yerri J, Kliachyna M, Baati R, Nachon F. Calas AG, et al. Biomolecules. 2020 Jun 4;10(6):858. doi: 10.3390/biom10060858. Biomolecules. 2020. PMID: 32512884 Free PMC article.
14 results