Cain K - Search Results

1

Transcriptional perturbation of protein arginine methyltransferase-5 exhibits MTAP-selective oncosuppression.

Busacca S, Zhang Q, Sharkey A, Dawson AG, Moore DA, Waller DA, Nakas A, Jones C, Cain K, Luo JL, Salcedo A, Salaroglio IC, Riganti C, Le Quesne J, John T, Boutros PC, Zhang SD, Fennell DA. Busacca S, et al. Among authors: cain k. Sci Rep. 2021 Apr 1;11(1):7434. doi: 10.1038/s41598-021-86834-7. Sci Rep. 2021. PMID: 33795785 Free PMC article.

2

Molecular profiling reveals primary mesothelioma cell lines recapitulate human disease.

Chernova T, Sun XM, Powley IR, Galavotti S, Grosso S, Murphy FA, Miles GJ, Cresswell L, Antonov AV, Bennett J, Nakas A, Dinsdale D, Cain K, Bushell M, Willis AE, MacFarlane M. Chernova T, et al. Among authors: cain k. Cell Death Differ. 2016 Jul;23(7):1152-64. doi: 10.1038/cdd.2015.165. Epub 2016 Feb 19. Cell Death Differ. 2016. PMID: 26891694 Free PMC article.

3

eIF4A2 drives repression of translation at initiation by Ccr4-Not through purine-rich motifs in the 5'UTR.

Wilczynska A, Gillen SL, Schmidt T, Meijer HA, Jukes-Jones R, Langlais C, Kopra K, Lu WT, Godfrey JD, Hawley BR, Hodge K, Zanivan S, Cain K, Le Quesne J, Bushell M. Wilczynska A, et al. Among authors: cain k. Genome Biol. 2019 Dec 2;20(1):262. doi: 10.1186/s13059-019-1857-2. Genome Biol. 2019. PMID: 31791371 Free PMC article.

4

The mTOR regulated RNA-binding protein LARP1 requires PABPC1 for guided mRNA interaction.

Smith EM, Benbahouche NEH, Morris K, Wilczynska A, Gillen S, Schmidt T, Meijer HA, Jukes-Jones R, Cain K, Jones C, Stoneley M, Waldron JA, Bell C, Fonseca BD, Blagden S, Willis AE, Bushell M. Smith EM, et al. Among authors: cain k. Nucleic Acids Res. 2021 Jan 11;49(1):458-478. doi: 10.1093/nar/gkaa1189. Nucleic Acids Res. 2021. PMID: 33332560 Free PMC article.

5

Switching from aerobic glycolysis to oxidative phosphorylation modulates the sensitivity of mantle cell lymphoma cells to TRAIL.

Robinson GL, Dinsdale D, Macfarlane M, Cain K. Robinson GL, et al. Among authors: cain k. Oncogene. 2012 Nov 29;31(48):4996-5006. doi: 10.1038/onc.2012.13. Epub 2012 Feb 6. Oncogene. 2012. PMID: 22310286

6

Processing/activation of at least four interleukin-1beta converting enzyme-like proteases occurs during the execution phase of apoptosis in human monocytic tumor cells.

MacFarlane M, Cain K, Sun XM, Alnemri ES, Cohen GM. MacFarlane M, et al. Among authors: cain k. J Cell Biol. 1997 Apr 21;137(2):469-79. doi: 10.1083/jcb.137.2.469. J Cell Biol. 1997. PMID: 9128256 Free PMC article.

7

Reconstitution of the death-inducing signaling complex reveals a substrate switch that determines CD95-mediated death or survival.

Hughes MA, Harper N, Butterworth M, Cain K, Cohen GM, MacFarlane M. Hughes MA, et al. Among authors: cain k. Mol Cell. 2009 Aug 14;35(3):265-79. doi: 10.1016/j.molcel.2009.06.012. Mol Cell. 2009. PMID: 19683492 Free article.

8

Protein complexes activate distinct caspase cascades in death receptor and stress-induced apoptosis.

Bratton SB, MacFarlane M, Cain K, Cohen GM. Bratton SB, et al. Among authors: cain k. Exp Cell Res. 2000 Apr 10;256(1):27-33. doi: 10.1006/excr.2000.4835. Exp Cell Res. 2000. PMID: 10739648 Review.

9

Caspase-7 is directly activated by the approximately 700-kDa apoptosome complex and is released as a stable XIAP-caspase-7 approximately 200-kDa complex.

Twiddy D, Cohen GM, Macfarlane M, Cain K. Twiddy D, et al. Among authors: cain k. J Biol Chem. 2006 Feb 17;281(7):3876-88. doi: 10.1074/jbc.M507393200. Epub 2005 Dec 13. J Biol Chem. 2006. PMID: 16352606 Free article.

10

Autophagy limits proliferation and glycolytic metabolism in acute myeloid leukemia.

Watson AS, Riffelmacher T, Stranks A, Williams O, De Boer J, Cain K, MacFarlane M, McGouran J, Kessler B, Khandwala S, Chowdhury O, Puleston D, Phadwal K, Mortensen M, Ferguson D, Soilleux E, Woll P, Jacobsen SE, Simon AK. Watson AS, et al. Among authors: cain k. Cell Death Discov. 2015 Aug 17;1:15008-. doi: 10.1038/cddiscovery.2015.8. Cell Death Discov. 2015. PMID: 26568842 Free PMC article.

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