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Attenuation of cGAS-STING signaling is mediated by a p62/SQSTM1-dependent autophagy pathway activated by TBK1.
Prabakaran T, Bodda C, Krapp C, Zhang BC, Christensen MH, Sun C, Reinert L, Cai Y, Jensen SB, Skouboe MK, Nyengaard JR, Thompson CB, Lebbink RJ, Sen GC, van Loo G, Nielsen R, Komatsu M, Nejsum LN, Jakobsen MR, Gyrd-Hansen M, Paludan SR. Prabakaran T, et al. Among authors: cai y. EMBO J. 2018 Apr 13;37(8):e97858. doi: 10.15252/embj.201797858. Epub 2018 Mar 1. EMBO J. 2018. PMID: 29496741 Free PMC article.
Efficient sleeping beauty DNA transposition from DNA minicircles.
Sharma N, Cai Y, Bak RO, Jakobsen MR, Schrøder LD, Mikkelsen JG. Sharma N, et al. Among authors: cai y. Mol Ther Nucleic Acids. 2013 Feb 26;2(2):e74. doi: 10.1038/mtna.2013.1. Mol Ther Nucleic Acids. 2013. PMID: 23443502 Free PMC article.
Inborn errors in RNA polymerase III underlie severe varicella zoster virus infections.
Ogunjimi B, Zhang SY, Sørensen KB, Skipper KA, Carter-Timofte M, Kerner G, Luecke S, Prabakaran T, Cai Y, Meester J, Bartholomeus E, Bolar NA, Vandeweyer G, Claes C, Sillis Y, Lorenzo L, Fiorenza RA, Boucherit S, Dielman C, Heynderickx S, Elias G, Kurotova A, Auwera AV, Verstraete L, Lagae L, Verhelst H, Jansen A, Ramet J, Suls A, Smits E, Ceulemans B, Van Laer L, Plat Wilson G, Kreth J, Picard C, Von Bernuth H, Fluss J, Chabrier S, Abel L, Mortier G, Fribourg S, Mikkelsen JG, Casanova JL, Paludan SR, Mogensen TH. Ogunjimi B, et al. Among authors: cai y. J Clin Invest. 2017 Sep 1;127(9):3543-3556. doi: 10.1172/JCI92280. Epub 2017 Aug 7. J Clin Invest. 2017. PMID: 28783042 Free PMC article.
STEEP mediates STING ER exit and activation of signaling.
Zhang BC, Nandakumar R, Reinert LS, Huang J, Laustsen A, Gao ZL, Sun CL, Jensen SB, Troldborg A, Assil S, Berthelsen MF, Scavenius C, Zhang Y, Windross SJ, Olagnier D, Prabakaran T, Bodda C, Narita R, Cai Y, Zhang CG, Stenmark H, Doucet CM, Noda T, Guo Z, Goldbach-Mansky R, Hartmann R, Chen ZJ, Enghild JJ, Bak RO, Thomsen MK, Paludan SR. Zhang BC, et al. Among authors: cai y. Nat Immunol. 2020 Aug;21(8):868-879. doi: 10.1038/s41590-020-0730-5. Epub 2020 Jul 20. Nat Immunol. 2020. PMID: 32690950 Free PMC article.
Author Correction: STEEP mediates STING ER exit and activation of signaling.
Zhang BC, Nandakumar R, Reinert LS, Huang J, Laustsen A, Gao ZL, Sun CL, Jensen SB, Troldborg A, Assil S, Berthelsen MF, Scavenius C, Zhang Y, Windross SJ, Olagnier D, Prabakaran T, Bodda C, Narita R, Cai Y, Zhang CG, Stenmark H, Doucet CM, Noda T, Guo Z, Goldbach-Mansky R, Hartmann R, Chen ZJ, Enghild JJ, Bak RO, Thomsen MK, Paludan SR. Zhang BC, et al. Among authors: cai y. Nat Immunol. 2020 Nov;21(11):1468-1469. doi: 10.1038/s41590-020-0803-5. Nat Immunol. 2020. PMID: 32929276
Essential role of autophagy in restricting poliovirus infection revealed by identification of an ATG7 defect in a poliomyelitis patient.
Brinck Andersen NS, Jørgensen SE, Skipper KA, Larsen SM, Heinz J, Thomsen MM, Farahani E, Cai Y, Hait AS, Kay L, Giehm Mikkelsen J, Høgsbjerg Schleimann M, Thomsen MK, Paludan SR, Mogensen TH. Brinck Andersen NS, et al. Among authors: cai y. Autophagy. 2021 Sep;17(9):2449-2464. doi: 10.1080/15548627.2020.1831800. Epub 2020 Oct 20. Autophagy. 2021. PMID: 33016799 Free PMC article.
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