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Mammalian SWI/SNF chromatin remodeling complexes promote tyrosine kinase inhibitor resistance in EGFR-mutant lung cancer.
de Miguel FJ, Gentile C, Feng WW, Silva SJ, Sankar A, Exposito F, Cai WL, Melnick MA, Robles-Oteiza C, Hinkley MM, Tsai JA, Hartley AV, Wei J, Wurtz A, Li F, Toki MI, Rimm DL, Homer R, Wilen CB, Xiao AZ, Qi J, Yan Q, Nguyen DX, Jänne PA, Kadoch C, Politi KA. de Miguel FJ, et al. Among authors: cai wl. Cancer Cell. 2023 Aug 14;41(8):1516-1534.e9. doi: 10.1016/j.ccell.2023.07.005. Epub 2023 Aug 3. Cancer Cell. 2023. PMID: 37541244 Free article.
The KDM6A-KMT2D-p300 axis regulates susceptibility to diverse coronaviruses by mediating viral receptor expression.
Wei J, Alfajaro MM, Cai WL, Graziano VR, Strine MS, Filler RB, Biering SB, Sarnik SA, Patel S, Menasche BL, Compton SR, Konermann S, Hsu PD, Orchard RC, Yan Q, Wilen CB. Wei J, et al. Among authors: cai wl. PLoS Pathog. 2023 Jul 6;19(7):e1011351. doi: 10.1371/journal.ppat.1011351. eCollection 2023 Jul. PLoS Pathog. 2023. PMID: 37410700 Free PMC article.
DYRK1A promotes viral entry of highly pathogenic human coronaviruses in a kinase-independent manner.
Strine MS, Cai WL, Wei J, Alfajaro MM, Filler RB, Biering SB, Sarnik S, Chow RD, Patil A, Cervantes KS, Collings CK, DeWeirdt PC, Hanna RE, Schofield K, Hulme C, Konermann S, Doench JG, Hsu PD, Kadoch C, Yan Q, Wilen CB. Strine MS, et al. Among authors: cai wl. PLoS Biol. 2023 Jun 13;21(6):e3002097. doi: 10.1371/journal.pbio.3002097. eCollection 2023 Jun. PLoS Biol. 2023. PMID: 37310920 Free PMC article.
Pharmacological disruption of mSWI/SNF complex activity restricts SARS-CoV-2 infection.
Wei J, Patil A, Collings CK, Alfajaro MM, Liang Y, Cai WL, Strine MS, Filler RB, DeWeirdt PC, Hanna RE, Menasche BL, Ökten A, Peña-Hernández MA, Klein J, McNamara A, Rosales R, McGovern BL, Luis Rodriguez M, García-Sastre A, White KM, Qin Y, Doench JG, Yan Q, Iwasaki A, Zwaka TP, Qi J, Kadoch C, Wilen CB. Wei J, et al. Among authors: cai wl. Nat Genet. 2023 Mar;55(3):471-483. doi: 10.1038/s41588-023-01307-z. Epub 2023 Mar 9. Nat Genet. 2023. PMID: 36894709 Free PMC article.
77 results