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Page 1
Molecular Profiling Reveals a Common Metabolic Signature of Tissue Fibrosis.
Zhang J, Muise ES, Han S, Kutchukian PS, Costet P, Zhu Y, Kan Y, Zhou H, Shah V, Huang Y, Saigal A, Akiyama TE, Shen XL, Cai TQ, Shah K, Carballo-Jane E, Zycband E, Yi L, Tian Y, Chen Y, Imbriglio J, Smith E, Devito K, Conway J, Ma LJ, Hoek M, Sebhat IK, Peier AM, Talukdar S, McLaren DG, Previs SF, Jensen KK, Pinto S. Zhang J, et al. Among authors: cai tq. Cell Rep Med. 2020 Jul 21;1(4):100056. doi: 10.1016/j.xcrm.2020.100056. eCollection 2020 Jul 21. Cell Rep Med. 2020. PMID: 33205063 Free PMC article.
Discovery of a new class of integrin antibodies for fibrosis.
Zhang J, Wang T, Saigal A, Johnson J, Morrisson J, Tabrizifard S, Hollingsworth SA, Eddins MJ, Mao W, O'Neill K, Garcia-Calvo M, Carballo-Jane E, Liu D, Ham T, Zhou Q, Dong W, Meng HW, Hicks J, Cai TQ, Akiyama T, Pinto S, Cheng AC, Greshock T, Marquis JC, Ren Z, Talukdar S, Shaheen HH, Handa M. Zhang J, et al. Among authors: cai tq. Sci Rep. 2021 Jan 22;11(1):2118. doi: 10.1038/s41598-021-81253-0. Sci Rep. 2021. PMID: 33483531 Free PMC article.
Differential anti-thrombotic benefit and bleeding risk profiles of antagonists of protease-activated receptor 1 and 4 in Cynomolgus Macaques.
Wickham LA, Sitko G, Stranieri-Michener M, Handt L, Basso A, Fried S, Chu L, Maderia M, Owens K, Castriota G, Chen Z, Metzger JM, Imbriglio J, Wang X, Cai TQ. Wickham LA, et al. Among authors: cai tq. Thromb Res. 2016 Sep;145:133-9. doi: 10.1016/j.thromres.2016.06.007. Epub 2016 Jun 11. Thromb Res. 2016. PMID: 27318768
Titrating haemophilia B phenotypes using siRNA strategy: evidence that antithrombotic activity is separated from bleeding liability.
Metzger JM, Tadin-Strapps M, Thankappan A, Strapps WR, DiPietro M, Leander K, Zhang Z, Shin MK, Levorse J, Desai K, Xu Y, Lai K, Wu W, Chen Z, Cai TQ, Jochnowitz N, Bentley R, Hoos L, Zhou Y, Sepp-Lorenzino L, Seiffert D, Andre P. Metzger JM, et al. Among authors: cai tq. Thromb Haemost. 2015 Jun;113(6):1300-11. doi: 10.1160/TH14-06-0505. Epub 2015 Mar 19. Thromb Haemost. 2015. PMID: 25790442
Proof-of-concept Studies for siRNA-mediated Gene Silencing for Coagulation Factors in Rat and Rabbit.
Chen Z, Luo B, Cai TQ, Thankappan A, Xu Y, Wu W, DiMuzio J, Lifsted T, DiPietro M, Disa J, Ng B, Leander K, Clark S, Hoos L, Zhou Y, Jochnowitz N, Jachec C, Szczerba P, Gindy ME, Strapps W, Sepp-Lorenzino L, Seiffert DA, Lubbers L, Tadin-Strapps M. Chen Z, et al. Among authors: cai tq. Mol Ther Nucleic Acids. 2015 Jan 27;4(1):e224. doi: 10.1038/mtna.2014.75. Mol Ther Nucleic Acids. 2015. PMID: 25625614 Free PMC article.
PGF2α signaling drives fibrotic remodeling and fibroblast population dynamics in mice.
Rodriguez LR, Tang SY, Roque Barboza W, Murthy A, Tomer Y, Cai TQ, Iyer S, Chavez K, Das US, Ghosh S, Cooper CH, Dimopoulos TT, Babu A, Connelly C, FitzGerald GA, Beers MF. Rodriguez LR, et al. Among authors: cai tq. JCI Insight. 2023 Dec 22;8(24):e172977. doi: 10.1172/jci.insight.172977. JCI Insight. 2023. PMID: 37934604 Free PMC article.
Disruption of Prostaglandin F2α Receptor Signaling Attenuates Fibrotic Remodeling and Alters Fibroblast Population Dynamics in A Preclinical Murine Model of Idiopathic Pulmonary Fibrosis.
Rodriguez LR, Tang SY, Barboza WR, Murthy A, Tomer Y, Cai TQ, Iyer S, Chavez K, Das US, Ghosh S, Dimopoulos T, Babu A, Connelly C, FitzGerald GA, Beers MF. Rodriguez LR, et al. Among authors: cai tq. bioRxiv [Preprint]. 2023 Jun 7:2023.06.07.543956. doi: 10.1101/2023.06.07.543956. bioRxiv. 2023. PMID: 37333249 Free PMC article. Preprint.
49 results