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Elevated hepatic multidrug resistance-associated protein 3/ATP-binding cassette subfamily C 3 expression in human obstructive cholestasis is mediated through tumor necrosis factor alpha and c-Jun NH2-terminal kinase/stress-activated protein kinase-signaling pathway.
Chai J, He Y, Cai SY, Jiang Z, Wang H, Li Q, Chen L, Peng Z, He X, Wu X, Xiao T, Wang R, Boyer JL, Chen W. Chai J, et al. Among authors: cai sy. Hepatology. 2012 May;55(5):1485-94. doi: 10.1002/hep.24801. Hepatology. 2012. PMID: 22105759 Free PMC article.
Runt-related transcription factor-1 ameliorates bile acid-induced hepatic inflammation in cholestasis through JAK/STAT3 signaling.
Zhang L, Pan Q, Zhang L, Xia H, Liao J, Zhang X, Zhao N, Xie Q, Liao M, Tan Y, Li Q, Zhu J, Li L, Fan S, Li J, Zhang C, Cai SY, Boyer JL, Chai J. Zhang L, et al. Among authors: cai sy. Hepatology. 2023 Jun 1;77(6):1866-1881. doi: 10.1097/HEP.0000000000000041. Epub 2023 Jan 3. Hepatology. 2023. PMID: 36647589 Free PMC article.
Unique DUOX2+ACE2+ small cholangiocytes are pathogenic targets for primary biliary cholangitis.
Li X, Li Y, Xiao J, Wang H, Guo Y, Mao X, Shi P, Hou Y, Zhang X, Zhao N, Zheng M, He Y, Ding J, Tan Y, Liao M, Li L, Peng Y, Li X, Pan Q, Xie Q, Li Q, Li J, Li Y, Chen Z, Huang Y, Assis DN, Cai SY, Boyer JL, Huang X, Tang CE, Liu X, Peng S, Chai J. Li X, et al. Among authors: cai sy. Nat Commun. 2023 Feb 9;14(1):29. doi: 10.1038/s41467-022-34606-w. Nat Commun. 2023. PMID: 36759512 Free PMC article.
Organic Anion Transporting Polypeptide (OATP) 1B3 is a Significant Transporter for Hepatic Uptake of Conjugated Bile Acids in Humans.
Pan Q, Zhu G, Xu Z, Zhu J, Ouyang J, Tong Y, Zhao N, Zhang X, Cheng Y, Zhang L, Tan Y, Li J, Zhang C, Chen W, Cai SY, Boyer JL, Chai J. Pan Q, et al. Among authors: cai sy. Cell Mol Gastroenterol Hepatol. 2023;16(2):223-242. doi: 10.1016/j.jcmgh.2023.04.007. Epub 2023 May 3. Cell Mol Gastroenterol Hepatol. 2023. PMID: 37146714 Free PMC article.
140 results