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Whole-mouse clearing and imaging at the cellular level with vDISCO.
Cai R, Kolabas ZI, Pan C, Mai H, Zhao S, Kaltenecker D, Voigt FF, Molbay M, Ohn TL, Vincke C, Todorov MI, Helmchen F, Van Ginderachter JA, Ertürk A. Cai R, et al. Nat Protoc. 2023 Apr;18(4):1197-1242. doi: 10.1038/s41596-022-00788-2. Epub 2023 Jan 25. Nat Protoc. 2023. PMID: 36697871 Review.
Shrinkage-mediated imaging of entire organs and organisms using uDISCO.
Pan C, Cai R, Quacquarelli FP, Ghasemigharagoz A, Lourbopoulos A, Matryba P, Plesnila N, Dichgans M, Hellal F, Ertürk A. Pan C, et al. Among authors: cai r. Nat Methods. 2016 Oct;13(10):859-67. doi: 10.1038/nmeth.3964. Epub 2016 Aug 22. Nat Methods. 2016. PMID: 27548807
Panoptic imaging of transparent mice reveals whole-body neuronal projections and skull-meninges connections.
Cai R, Pan C, Ghasemigharagoz A, Todorov MI, Förstera B, Zhao S, Bhatia HS, Parra-Damas A, Mrowka L, Theodorou D, Rempfler M, Xavier ALR, Kress BT, Benakis C, Steinke H, Liebscher S, Bechmann I, Liesz A, Menze B, Kerschensteiner M, Nedergaard M, Ertürk A. Cai R, et al. Nat Neurosci. 2019 Feb;22(2):317-327. doi: 10.1038/s41593-018-0301-3. Epub 2018 Dec 31. Nat Neurosci. 2019. PMID: 30598527 Free PMC article.
Deep Learning Reveals Cancer Metastasis and Therapeutic Antibody Targeting in the Entire Body.
Pan C, Schoppe O, Parra-Damas A, Cai R, Todorov MI, Gondi G, von Neubeck B, Böğürcü-Seidel N, Seidel S, Sleiman K, Veltkamp C, Förstera B, Mai H, Rong Z, Trompak O, Ghasemigharagoz A, Reimer MA, Cuesta AM, Coronel J, Jeremias I, Saur D, Acker-Palmer A, Acker T, Garvalov BK, Menze B, Zeidler R, Ertürk A. Pan C, et al. Among authors: cai r. Cell. 2019 Dec 12;179(7):1661-1676.e19. doi: 10.1016/j.cell.2019.11.013. Cell. 2019. PMID: 31835038 Free PMC article.
Cellular and Molecular Probing of Intact Human Organs.
Zhao S, Todorov MI, Cai R, -Maskari RA, Steinke H, Kemter E, Mai H, Rong Z, Warmer M, Stanic K, Schoppe O, Paetzold JC, Gesierich B, Wong MN, Huber TB, Duering M, Bruns OT, Menze B, Lipfert J, Puelles VG, Wolf E, Bechmann I, Ertürk A. Zhao S, et al. Among authors: cai r. Cell. 2020 Feb 20;180(4):796-812.e19. doi: 10.1016/j.cell.2020.01.030. Epub 2020 Feb 13. Cell. 2020. PMID: 32059778 Free PMC article.
Selective plasticity of callosal neurons in the adult contralesional cortex following murine traumatic brain injury.
Empl L, Chovsepian A, Chahin M, Kan WYV, Fourneau J, Van Steenbergen V, Weidinger S, Marcantoni M, Ghanem A, Bradley P, Conzelmann KK, Cai R, Ghasemigharagoz A, Ertürk A, Wagner I, Kreutzfeldt M, Merkler D, Liebscher S, Bareyre FM. Empl L, et al. Among authors: cai r. Nat Commun. 2022 May 12;13(1):2659. doi: 10.1038/s41467-022-29992-0. Nat Commun. 2022. PMID: 35551446 Free PMC article.
Scalable tissue labeling and clearing of intact human organs.
Mai H, Rong Z, Zhao S, Cai R, Steinke H, Bechmann I, Ertürk A. Mai H, et al. Among authors: cai r. Nat Protoc. 2022 Oct;17(10):2188-2215. doi: 10.1038/s41596-022-00712-8. Epub 2022 Jul 20. Nat Protoc. 2022. PMID: 35859136 Review.
The Benchtop mesoSPIM: a next-generation open-source light-sheet microscope for large cleared samples.
Vladimirov N, Voigt FF, Naert T, Araujo GR, Cai R, Reuss AM, Zhao S, Schmid P, Hildebrand S, Schaettin M, Groos D, Mateos JM, Bethge P, Yamamoto T, Aerne V, Roebroeck A, Ertürk A, Aguzzi A, Ziegler U, Stoeckli E, Baudis L, Lienkamp SS, Helmchen F. Vladimirov N, et al. Among authors: cai r. bioRxiv [Preprint]. 2023 Dec 12:2023.06.16.545256. doi: 10.1101/2023.06.16.545256. bioRxiv. 2023. PMID: 38168219 Free PMC article. Updated. Preprint.
Benchtop mesoSPIM: a next-generation open-source light-sheet microscope for cleared samples.
Vladimirov N, Voigt FF, Naert T, Araujo GR, Cai R, Reuss AM, Zhao S, Schmid P, Hildebrand S, Schaettin M, Groos D, Mateos JM, Bethge P, Yamamoto T, Aerne V, Roebroeck A, Ertürk A, Aguzzi A, Ziegler U, Stoeckli E, Baudis L, Lienkamp SS, Helmchen F. Vladimirov N, et al. Among authors: cai r. Nat Commun. 2024 Mar 27;15(1):2679. doi: 10.1038/s41467-024-46770-2. Nat Commun. 2024. PMID: 38538644 Free PMC article.
2,282 results