Cai L - Search Results

1

ARN-509: a novel antiandrogen for prostate cancer treatment.

Clegg NJ, Wongvipat J, Joseph JD, Tran C, Ouk S, Dilhas A, Chen Y, Grillot K, Bischoff ED, Cai L, Aparicio A, Dorow S, Arora V, Shao G, Qian J, Zhao H, Yang G, Cao C, Sensintaffar J, Wasielewska T, Herbert MR, Bonnefous C, Darimont B, Scher HI, Smith-Jones P, Klang M, Smith ND, De Stanchina E, Wu N, Ouerfelli O, Rix PJ, Heyman RA, Jung ME, Sawyers CL, Hager JH. Clegg NJ, et al. Among authors: cai l. Cancer Res. 2012 Mar 15;72(6):1494-503. doi: 10.1158/0008-5472.CAN-11-3948. Epub 2012 Jan 20. Cancer Res. 2012. PMID: 22266222 Free PMC article.

2

Transcriptional regulation of a metastasis suppressor gene by Tip60 and beta-catenin complexes.

Kim JH, Kim B, Cai L, Choi HJ, Ohgi KA, Tran C, Chen C, Chung CH, Huber O, Rose DW, Sawyers CL, Rosenfeld MG, Baek SH. Kim JH, et al. Among authors: cai l. Nature. 2005 Apr 14;434(7035):921-6. doi: 10.1038/nature03452. Nature. 2005. PMID: 15829968 Free article.

3

Androgen receptor signaling regulates DNA repair in prostate cancers.

Polkinghorn WR, Parker JS, Lee MX, Kass EM, Spratt DE, Iaquinta PJ, Arora VK, Yen WF, Cai L, Zheng D, Carver BS, Chen Y, Watson PA, Shah NP, Fujisawa S, Goglia AG, Gopalan A, Hieronymus H, Wongvipat J, Scardino PT, Zelefsky MJ, Jasin M, Chaudhuri J, Powell SN, Sawyers CL. Polkinghorn WR, et al. Among authors: cai l. Cancer Discov. 2013 Nov;3(11):1245-53. doi: 10.1158/2159-8290.CD-13-0172. Epub 2013 Sep 11. Cancer Discov. 2013. PMID: 24027196 Free PMC article.

4

Glucocorticoid receptor confers resistance to antiandrogens by bypassing androgen receptor blockade.

Arora VK, Schenkein E, Murali R, Subudhi SK, Wongvipat J, Balbas MD, Shah N, Cai L, Efstathiou E, Logothetis C, Zheng D, Sawyers CL. Arora VK, et al. Among authors: cai l. Cell. 2013 Dec 5;155(6):1309-22. doi: 10.1016/j.cell.2013.11.012. Cell. 2013. PMID: 24315100 Free PMC article.

5

A Model System for Studying the DNMT3A Hotspot Mutation (DNMT3A^R882) Demonstrates a Causal Relationship between Its Dominant-Negative Effect and Leukemogenesis.

Lu R, Wang J, Ren Z, Yin J, Wang Y, Cai L, Wang GG. Lu R, et al. Among authors: cai l. Cancer Res. 2019 Jul 15;79(14):3583-3594. doi: 10.1158/0008-5472.CAN-18-3275. Epub 2019 Jun 4. Cancer Res. 2019. PMID: 31164355 Free PMC article.

6

Author Correction: Transcriptional regulation of a metastasis suppressor gene by Tip60 and β-catenin complexes.

Kim JH, Kim B, Cai L, Choi HJ, Ohgi KA, Tran C, Chen C, Chung CH, Huber O, Rose DW, Sawyers CL, Rosenfeld MG, Baek SH. Kim JH, et al. Among authors: cai l. Nature. 2022 Jul;607(7919):E11. doi: 10.1038/s41586-022-04945-1. Nature. 2022. PMID: 35790797 No abstract available.

7

ZFX Mediates Non-canonical Oncogenic Functions of the Androgen Receptor Splice Variant 7 in Castrate-Resistant Prostate Cancer.

Cai L, Tsai YH, Wang P, Wang J, Li D, Fan H, Zhao Y, Bareja R, Lu R, Wilson EM, Sboner A, Whang YE, Zheng D, Parker JS, Earp HS, Wang GG. Cai L, et al. Mol Cell. 2018 Oct 18;72(2):341-354.e6. doi: 10.1016/j.molcel.2018.08.029. Epub 2018 Sep 27. Mol Cell. 2018. PMID: 30270106 Free PMC article.

8

A cryptic transactivation domain of EZH2 binds AR and AR's splice variant, promoting oncogene activation and tumorous transformation.

Wang J, Park KS, Yu X, Gong W, Earp HS, Wang GG, Jin J, Cai L. Wang J, et al. Among authors: cai l. Nucleic Acids Res. 2022 Oct 28;50(19):10929-10946. doi: 10.1093/nar/gkac861. Nucleic Acids Res. 2022. PMID: 36300627 Free PMC article.

9

Interaction between androgen receptor and coregulator SLIRP is regulated by Ack1 tyrosine kinase and androgen.

De Silva D, Zhang Z, Liu Y, Parker JS, Xu C, Cai L, Wang GG, Earp HS, Whang YE. De Silva D, et al. Among authors: cai l. Sci Rep. 2019 Dec 9;9(1):18637. doi: 10.1038/s41598-019-55057-2. Sci Rep. 2019. PMID: 31819114 Free PMC article.

10

Cistrome analysis of YY1 uncovers a regulatory axis of YY1:BRD2/4-PFKP during tumorigenesis of advanced prostate cancer.

Xu C, Tsai YH, Galbo PM, Gong W, Storey AJ, Xu Y, Byrum SD, Xu L, Whang YE, Parker JS, Mackintosh SG, Edmondson RD, Tackett AJ, Huang J, Zheng D, Earp HS, Wang GG, Cai L. Xu C, et al. Among authors: cai l. Nucleic Acids Res. 2021 May 21;49(9):4971-4988. doi: 10.1093/nar/gkab252. Nucleic Acids Res. 2021. PMID: 33849067 Free PMC article.

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