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Discovery of small-molecule activators of nicotinamide phosphoribosyltransferase (NAMPT) and their preclinical neuroprotective activity.
Yao H, Liu M, Wang L, Zu Y, Wu C, Li C, Zhang R, Lu H, Li F, Xi S, Chen S, Gu X, Liu T, Cai J, Wang S, Yang M, Xing GG, Xiong W, Hua L, Tang Y, Wang G. Yao H, et al. Among authors: cai j. Cell Res. 2022 Jun;32(6):570-584. doi: 10.1038/s41422-022-00651-9. Epub 2022 Apr 22. Cell Res. 2022. PMID: 35459935 Free PMC article.
Down-regulation of CatSper1 channel in epididymal spermatozoa contributes to the pathogenesis of asthenozoospermia, whereas up-regulation of the channel by Sheng-Jing-San treatment improves the sperm motility of asthenozoospermia in rats.
Wang YN, Wang B, Liang M, Han CY, Zhang B, Cai J, Sun W, Xing GG. Wang YN, et al. Among authors: cai j. Fertil Steril. 2013 Feb;99(2):579-87. doi: 10.1016/j.fertnstert.2012.10.030. Epub 2012 Nov 10. Fertil Steril. 2013. PMID: 23148924 Clinical Trial.
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