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Epigenetic silencing of GCH1promotes hepatocellular carcinoma growth by activating superoxide anion-mediated ASK1/p38 signaling via inhibiting tetrahydrobiopterin de novo biosynthesis.
Zhong GC, Zhao ZB, Cheng Y, Wang YB, Qiu C, Mao LH, Hu JJ, Cai D, Liu Y, Gong JP, Li SW. Zhong GC, et al. Among authors: cai d. Free Radic Biol Med. 2021 May 20;168:81-94. doi: 10.1016/j.freeradbiomed.2021.03.025. Epub 2021 Mar 26. Free Radic Biol Med. 2021. PMID: 33781891
Inhibiting cholesterol de novo synthesis promotes hepatocellular carcinoma progression by upregulating prostaglandin E synthase 2-mediated arachidonic acid metabolism under high fatty acid conditions.
Zhao Z, Liu X, Xiang Y, Hou Z, He K, Zhong G, Hu J, Cai D, Liu Y, Ren J, Gong J, Zhao L. Zhao Z, et al. Among authors: cai d. Cancer Sci. 2024 Feb;115(2):477-489. doi: 10.1111/cas.16035. Epub 2023 Dec 11. Cancer Sci. 2024. PMID: 38081591 Free PMC article.
3,021 results