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Specific targeting of peripheral serotonin 5-HT(3) receptors. Synthesis, biological investigation, and structure-activity relationships.
Morelli E, Gemma S, Budriesi R, Campiani G, Novellino E, Fattorusso C, Catalanotti B, Coccone SS, Ros S, Borrelli G, Persico M, Fiorini I, Nacci V, Ioan P, Chiarini A, Hamon M, Cagnotto A, Mennini T, Fracasso C, Colovic M, Caccia S, Butini S. Morelli E, et al. Among authors: cagnotto a. J Med Chem. 2009 Jun 11;52(11):3548-62. doi: 10.1021/jm900018b. J Med Chem. 2009. PMID: 19425598
Characterization of the 1H-cyclopentapyrimidine-2,4(1H,3H)-dione derivative (S)-CPW399 as a novel, potent, and subtype-selective AMPA receptor full agonist with partial desensitization properties.
Campiani G, Morelli E, Nacci V, Fattorusso C, Ramunno A, Novellino E, Greenwood J, Liljefors T, Griffiths R, Sinclair C, Reavy H, Kristensen AS, Pickering DS, Schousboe A, Cagnotto A, Fumagalli E, Mennini T. Campiani G, et al. Among authors: cagnotto a. J Med Chem. 2001 Dec 20;44(26):4501-4. doi: 10.1021/jm015552m. J Med Chem. 2001. PMID: 11741469
Structure-activity study of 2,3-benzodiazepin-4-ones noncompetitive AMPAR antagonists: identification of the 1-(4-amino-3-methylphenyl)-3,5-dihydro-7,8-ethylenedioxy-4H-2,3-benzodiazepin-4-one as neuroprotective agent.
Micale N, Colleoni S, Postorino G, Pellicanò A, Zappalà M, Lazzaro J, Diana V, Cagnotto A, Mennini T, Grasso S. Micale N, et al. Among authors: cagnotto a. Bioorg Med Chem. 2008 Mar 1;16(5):2200-11. doi: 10.1016/j.bmc.2007.11.080. Epub 2007 Dec 5. Bioorg Med Chem. 2008. PMID: 18083036
115 results