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A rationally designed NRP1-independent superagonist SEMA3A mutant is an effective anticancer agent.
Gioelli N, Maione F, Camillo C, Ghitti M, Valdembri D, Morello N, Darche M, Zentilin L, Cagnoni G, Qiu Y, Giacca M, Giustetto M, Paques M, Cascone I, Musco G, Tamagnone L, Giraudo E, Serini G. Gioelli N, et al. Among authors: cagnoni g. Sci Transl Med. 2018 May 23;10(442):eaah4807. doi: 10.1126/scitranslmed.aah4807. Sci Transl Med. 2018. PMID: 29794061 Free article.
Neuropilin-1 upregulation elicits adaptive resistance to oncogene-targeted therapies.
Rizzolio S, Cagnoni G, Battistini C, Bonelli S, Isella C, Van Ginderachter JA, Bernards R, Di Nicolantonio F, Giordano S, Tamagnone L. Rizzolio S, et al. Among authors: cagnoni g. J Clin Invest. 2018 Aug 31;128(9):3976-3990. doi: 10.1172/JCI99257. Epub 2018 Aug 13. J Clin Invest. 2018. PMID: 29953416 Free PMC article.
Brain endothelial cells control fertility through ovarian-steroid-dependent release of semaphorin 3A.
Giacobini P, Parkash J, Campagne C, Messina A, Casoni F, Vanacker C, Langlet F, Hobo B, Cagnoni G, Gallet S, Hanchate NK, Mazur D, Taniguchi M, Mazzone M, Verhaagen J, Ciofi P, Bouret SG, Tamagnone L, Prevot V. Giacobini P, et al. Among authors: cagnoni g. PLoS Biol. 2014 Mar 11;12(3):e1001808. doi: 10.1371/journal.pbio.1001808. eCollection 2014 Mar. PLoS Biol. 2014. PMID: 24618750 Free PMC article.
Semaphorin7A regulates neuroglial plasticity in the adult hypothalamic median eminence.
Parkash J, Messina A, Langlet F, Cimino I, Loyens A, Mazur D, Gallet S, Balland E, Malone SA, Pralong F, Cagnoni G, Schellino R, De Marchis S, Mazzone M, Pasterkamp RJ, Tamagnone L, Prevot V, Giacobini P. Parkash J, et al. Among authors: cagnoni g. Nat Commun. 2015 Feb 27;6:6385. doi: 10.1038/ncomms7385. Nat Commun. 2015. PMID: 25721933 Free PMC article.
Dysregulation of Semaphorin7A/β1-integrin signaling leads to defective GnRH-1 cell migration, abnormal gonadal development and altered fertility.
Messina A, Ferraris N, Wray S, Cagnoni G, Donohue DE, Casoni F, Kramer PR, Derijck AA, Adolfs Y, Fasolo A, Pasterkamp RJ, Giacobini P. Messina A, et al. Among authors: cagnoni g. Hum Mol Genet. 2011 Dec 15;20(24):4759-74. doi: 10.1093/hmg/ddr403. Epub 2011 Sep 8. Hum Mol Genet. 2011. PMID: 21903667 Free PMC article.
Similar outcome of tricuspid valve repair and replacement for isolated tricuspid infective endocarditis.
Di Mauro M, Bonalumi G, Giambuzzi I, Dato GMA, Centofanti P, Corte AD, Ratta ED, Cugola D, Merlo M, Santini F, Salsano A, Rinaldi M, Mancuso S, Cappabianca G, Beghi C, De Vincentiis C, Biondi A, Livi U, Sponga S, Pacini D, Murana G, Scrofani R, Antona C, Cagnoni G, Nicolini F, Benassi F, De Bonis M, Pozzoli A, Pano M, Nicolardi S, Falcetta G, Colli A, Musumeci F, Gherli R, Vizzardi E, Salvador L, Picichè M, Paparella D, Margari V, Troise G, Villa E, Dossena Y, Lucarelli C, Onorati F, Faggian G, Mariscalco G, Maselli D, Barili F, Parolari A, Lorusso R; Italian Group of Research for Outcome in Cardiac Surgery (GIROC). Di Mauro M, et al. Among authors: cagnoni g. J Cardiovasc Med (Hagerstown). 2022 Jun 1;23(6):406-413. doi: 10.2459/JCM.0000000000001310. J Cardiovasc Med (Hagerstown). 2022. PMID: 35645032
Surgery for Bentall endocarditis: short- and midterm outcomes from a multicentre registry.
Sponga S, Di Mauro M, Malvindi PG, Paparella D, Murana G, Pacini D, Weltert L, De Paulis R, Cappabianca G, Beghi C, De Vincentiis C, Parolari A, Messina A, Troise G, Salsano A, Santini F, Pierri MD, Di Eusanio M, Maselli D, Actis Dato G, Centofanti P, Mancuso S, Rinaldi M, Cagnoni G, Antona C, Picichè M, Salvador L, Cugola D, Galletti L, Pozzoli A, De Bonis M, Lorusso R, Bortolotti U, Livi U; Italian Group of Research for Outcome in Cardiac Surgery (GIROC). Sponga S, et al. Among authors: cagnoni g. Eur J Cardiothorac Surg. 2020 Oct 1;58(4):839-846. doi: 10.1093/ejcts/ezaa136. Eur J Cardiothorac Surg. 2020. PMID: 32417897
48 results