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Antiparasitic Properties of Propolis Extracts and Their Compounds.
de L Paula LA, Cândido ACBB, Santos MFC, Caffrey CR, Bastos JK, Ambrósio SR, Magalhães LG. de L Paula LA, et al. Among authors: caffrey cr. Chem Biodivers. 2021 Sep;18(9):e2100310. doi: 10.1002/cbdv.202100310. Epub 2021 Jul 28. Chem Biodivers. 2021. PMID: 34231306 Review.
EF24, a schistosomicidal curcumin analog: Insights from its synthesis and phenotypic, biochemical and cytotoxic activities.
Badoco FR, Paula LAL, Orenha RP, Mendes TMF, Squarisi IS, El-Sakkary N, Loiola MC, Katz N, Tavares DC, Sairre MI, Parreira RLT, Janku Cabral F, Alegretti SM, Caffrey CR, Magalhães LG. Badoco FR, et al. Among authors: caffrey cr. Chem Biol Interact. 2022 Dec 1;368:110191. doi: 10.1016/j.cbi.2022.110191. Epub 2022 Sep 28. Chem Biol Interact. 2022. PMID: 36181831 Free article.
Bis-acridines as lead antiparasitic agents: structure-activity analysis of a discrete compound library in vitro.
Caffrey CR, Steverding D, Swenerton RK, Kelly B, Walshe D, Debnath A, Zhou YM, Doyle PS, Fafarman AT, Zorn JA, Land KM, Beauchene J, Schreiber K, Moll H, Ponte-Sucre A, Schirmeister T, Saravanamuthu A, Fairlamb AH, Cohen FE, McKerrow JH, Weisman JL, May BC. Caffrey CR, et al. Antimicrob Agents Chemother. 2007 Jun;51(6):2164-72. doi: 10.1128/AAC.01418-06. Epub 2007 Mar 19. Antimicrob Agents Chemother. 2007. PMID: 17371810 Free PMC article.
Targeting proteasomes in infectious organisms to combat disease.
Bibo-Verdugo B, Jiang Z, Caffrey CR, O'Donoghue AJ. Bibo-Verdugo B, et al. Among authors: caffrey cr. FEBS J. 2017 May;284(10):1503-1517. doi: 10.1111/febs.14029. Epub 2017 Feb 16. FEBS J. 2017. PMID: 28122162 Free article. Review.
Discovery and characterization of trypanocidal cysteine protease inhibitors from the 'malaria box'.
Pereira GAN, da Silva EB, Braga SFP, Leite PG, Martins LC, Vieira RP, Soh WT, Villela FS, Costa FMR, Ray D, de Andrade SF, Brandstetter H, Oliveira RB, Caffrey CR, Machado FS, Ferreira RS. Pereira GAN, et al. Among authors: caffrey cr. Eur J Med Chem. 2019 Oct 1;179:765-778. doi: 10.1016/j.ejmech.2019.06.062. Epub 2019 Jun 22. Eur J Med Chem. 2019. PMID: 31284086 Free PMC article.
Hit-to-Lead Optimization of Benzoxazepinoindazoles As Human African Trypanosomiasis Therapeutics.
Klug DM, Tschiegg L, Diaz R, Rojas-Barros D, Perez-Moreno G, Ceballos G, García-Hernández R, Martinez-Martinez MS, Manzano P, Ruiz LM, Caffrey CR, Gamarro F, Pacanowska DG, Ferrins L, Navarro M, Pollastri MP. Klug DM, et al. Among authors: caffrey cr. J Med Chem. 2020 Mar 12;63(5):2527-2546. doi: 10.1021/acs.jmedchem.9b01506. Epub 2019 Nov 20. J Med Chem. 2020. PMID: 31670951 Free PMC article.
174 results