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Nanoscavenger provides long-term prophylactic protection against nerve agents in rodents.
Zhang P, Liu EJ, Tsao C, Kasten SA, Boeri MV, Dao TL, DeBus SJ, Cadieux CL, Baker CA, Otto TC, Cerasoli DM, Chen Y, Jain P, Sun F, Li W, Hung HC, Yuan Z, Ma J, Bigley AN, Raushel FM, Jiang S. Zhang P, et al. Among authors: cadieux cl. Sci Transl Med. 2019 Jan 2;11(473):eaau7091. doi: 10.1126/scitranslmed.aau7091. Sci Transl Med. 2019. PMID: 30602537
Plant-derived human butyrylcholinesterase, but not an organophosphorous-compound hydrolyzing variant thereof, protects rodents against nerve agents.
Geyer BC, Kannan L, Garnaud PE, Broomfield CA, Cadieux CL, Cherni I, Hodgins SM, Kasten SA, Kelley K, Kilbourne J, Oliver ZP, Otto TC, Puffenberger I, Reeves TE, Robbins N 2nd, Woods RR, Soreq H, Lenz DE, Cerasoli DM, Mor TS. Geyer BC, et al. Among authors: cadieux cl. Proc Natl Acad Sci U S A. 2010 Nov 23;107(47):20251-6. doi: 10.1073/pnas.1009021107. Epub 2010 Nov 8. Proc Natl Acad Sci U S A. 2010. PMID: 21059932 Free PMC article.
30 results