Cachau R - Search Results

1

Dromedary camel nanobodies broadly neutralize SARS-CoV-2 variants.

Hong J, Kwon HJ, Cachau R, Chen CZ, Butay KJ, Duan Z, Li D, Ren H, Liang T, Zhu J, Dandey VP, Martin NP, Esposito D, Ortega-Rodriguez U, Xu M, Borgnia MJ, Xie H, Ho M. Hong J, et al. Among authors: cachau r. Proc Natl Acad Sci U S A. 2022 May 3;119(18):e2201433119. doi: 10.1073/pnas.2201433119. Epub 2022 Apr 27. Proc Natl Acad Sci U S A. 2022. PMID: 35476528 Free PMC article.

2

The upcoming subatomic resolution revolution.

Cachau RE, Zhu J, Nicklaus MC. Cachau RE, et al. Curr Opin Struct Biol. 2019 Oct;58:53-58. doi: 10.1016/j.sbi.2019.05.013. Epub 2019 Jun 21. Curr Opin Struct Biol. 2019. PMID: 31233975 Review.

3

CAR T cells targeting tumor-associated exons of glypican 2 regress neuroblastoma in mice.

Li N, Torres MB, Spetz MR, Wang R, Peng L, Tian M, Dower CM, Nguyen R, Sun M, Tai CH, de Val N, Cachau R, Wu X, Hewitt SM, Kaplan RN, Khan J, St Croix B, Thiele CJ, Ho M. Li N, et al. Among authors: cachau r. Cell Rep Med. 2021 Jun 1;2(6):100297. doi: 10.1016/j.xcrm.2021.100297. eCollection 2021 Jun 15. Cell Rep Med. 2021. PMID: 34195677 Free PMC article.

4

The IgG4 hinge with CD28 transmembrane domain improves V_HH-based CAR T cells targeting a membrane-distal epitope of GPC1 in pancreatic cancer.

Li N, Quan A, Li D, Pan J, Ren H, Hoeltzel G, de Val N, Ashworth D, Ni W, Zhou J, Mackay S, Hewitt SM, Cachau R, Ho M. Li N, et al. Among authors: cachau r. Nat Commun. 2023 Apr 8;14(1):1986. doi: 10.1038/s41467-023-37616-4. Nat Commun. 2023. PMID: 37031249 Free PMC article.

5

Crystal structures of native and inhibited forms of human cathepsin D: implications for lysosomal targeting and drug design.

Baldwin ET, Bhat TN, Gulnik S, Hosur MV, Sowder RC 2nd, Cachau RE, Collins J, Silva AM, Erickson JW. Baldwin ET, et al. Among authors: cachau re. Proc Natl Acad Sci U S A. 1993 Jul 15;90(14):6796-800. doi: 10.1073/pnas.90.14.6796. Proc Natl Acad Sci U S A. 1993. PMID: 8393577 Free PMC article.

6

Structure and inhibition of plasmepsin II, a hemoglobin-degrading enzyme from Plasmodium falciparum.

Silva AM, Lee AY, Gulnik SV, Maier P, Collins J, Bhat TN, Collins PJ, Cachau RE, Luker KE, Gluzman IY, Francis SE, Oksman A, Goldberg DE, Erickson JW. Silva AM, et al. Among authors: cachau re. Proc Natl Acad Sci U S A. 1996 Sep 17;93(19):10034-9. doi: 10.1073/pnas.93.19.10034. Proc Natl Acad Sci U S A. 1996. PMID: 8816746 Free PMC article.

7

High-resolution crystallography and drug design.

Cachau RE, Podjarny AD. Cachau RE, et al. J Mol Recognit. 2005 May-Jun;18(3):196-202. doi: 10.1002/jmr.738. J Mol Recognit. 2005. PMID: 15782396 Review.

8

PDB ligand conformational energies calculated quantum-mechanically.

Sitzmann M, Weidlich IE, Filippov IV, Liao C, Peach ML, Ihlenfeldt WD, Karki RG, Borodina YV, Cachau RE, Nicklaus MC. Sitzmann M, et al. J Chem Inf Model. 2012 Mar 26;52(3):739-56. doi: 10.1021/ci200595n. Epub 2012 Feb 21. J Chem Inf Model. 2012. PMID: 22303903 Free PMC article.

9

Conformational energy range of ligands in protein crystal structures: The difficult quest for accurate understanding.

Peach ML, Cachau RE, Nicklaus MC. Peach ML, et al. J Mol Recognit. 2017 Aug;30(8):10.1002/jmr.2618. doi: 10.1002/jmr.2618. Epub 2017 Feb 24. J Mol Recognit. 2017. PMID: 28233410 Free PMC article. Review.

10

Ion channels in icosahedral virus: a comparative analysis of the structures and binding sites at their fivefold axes.

Kalko SG, Cachau RE, Silva AM. Kalko SG, et al. Among authors: cachau re. Biophys J. 1992 Oct;63(4):1133-45. doi: 10.1016/S0006-3495(92)81693-4. Biophys J. 1992. PMID: 1384743 Free PMC article.

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