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Cellular population dynamics shape the route to human pluripotency.
Panariello F, Gagliano O, Luni C, Grimaldi A, Angiolillo S, Qin W, Manfredi A, Annunziata P, Slovin S, Vaccaro L, Riccardo S, Bouche V, Dionisi M, Salvi M, Martewicz S, Hu M, Cui M, Stuart H, Laterza C, Baruzzo G, Schiebinger G, Di Camillo B, Cacchiarelli D, Elvassore N. Panariello F, et al. Among authors: cacchiarelli d. Nat Commun. 2023 May 17;14(1):2829. doi: 10.1038/s41467-023-37270-w. Nat Commun. 2023. PMID: 37198156 Free PMC article.
Triple Vectors Expand AAV Transfer Capacity in the Retina.
Maddalena A, Tornabene P, Tiberi P, Minopoli R, Manfredi A, Mutarelli M, Rossi S, Simonelli F, Naggert JK, Cacchiarelli D, Auricchio A. Maddalena A, et al. Among authors: cacchiarelli d. Mol Ther. 2018 Feb 7;26(2):524-541. doi: 10.1016/j.ymthe.2017.11.019. Epub 2017 Dec 5. Mol Ther. 2018. PMID: 29292161 Free PMC article.
Genome-wide tracking of dCas9-methyltransferase footprints.
Galonska C, Charlton J, Mattei AL, Donaghey J, Clement K, Gu H, Mohammad AW, Stamenova EK, Cacchiarelli D, Klages S, Timmermann B, Cantz T, Schöler HR, Gnirke A, Ziller MJ, Meissner A. Galonska C, et al. Among authors: cacchiarelli d. Nat Commun. 2018 Feb 9;9(1):597. doi: 10.1038/s41467-017-02708-5. Nat Commun. 2018. PMID: 29426832 Free PMC article.
Aligning Single-Cell Developmental and Reprogramming Trajectories Identifies Molecular Determinants of Myogenic Reprogramming Outcome.
Cacchiarelli D, Qiu X, Srivatsan S, Manfredi A, Ziller M, Overbey E, Grimaldi A, Grimsby J, Pokharel P, Livak KJ, Li S, Meissner A, Mikkelsen TS, Rinn JL, Trapnell C. Cacchiarelli D, et al. Cell Syst. 2018 Sep 26;7(3):258-268.e3. doi: 10.1016/j.cels.2018.07.006. Epub 2018 Sep 5. Cell Syst. 2018. PMID: 30195438 Free article.
Extracellular matrix hydrogel derived from decellularized tissues enables endodermal organoid culture.
Giobbe GG, Crowley C, Luni C, Campinoti S, Khedr M, Kretzschmar K, De Santis MM, Zambaiti E, Michielin F, Meran L, Hu Q, van Son G, Urbani L, Manfredi A, Giomo M, Eaton S, Cacchiarelli D, Li VSW, Clevers H, Bonfanti P, Elvassore N, De Coppi P. Giobbe GG, et al. Among authors: cacchiarelli d. Nat Commun. 2019 Dec 11;10(1):5658. doi: 10.1038/s41467-019-13605-4. Nat Commun. 2019. PMID: 31827102 Free PMC article.
The Microfluidic Environment Reveals a Hidden Role of Self-Organizing Extracellular Matrix in Hepatic Commitment and Organoid Formation of hiPSCs.
Michielin F, Giobbe GG, Luni C, Hu Q, Maroni I, Orford MR, Manfredi A, Di Filippo L, David AL, Cacchiarelli D, De Coppi P, Eaton S, Elvassore N. Michielin F, et al. Among authors: cacchiarelli d. Cell Rep. 2020 Dec 1;33(9):108453. doi: 10.1016/j.celrep.2020.108453. Cell Rep. 2020. PMID: 33264615 Free PMC article.
Integrated Genomics Identifies miR-181/TFAM Pathway as a Critical Driver of Drug Resistance in Melanoma.
Barbato A, Iuliano A, Volpe M, D'Alterio R, Brillante S, Massa F, De Cegli R, Carrella S, Salati M, Russo A, Russo G, Riccardo S, Cacchiarelli D, Capone M, Madonna G, Ascierto PA, Franco B, Indrieri A, Carotenuto P. Barbato A, et al. Among authors: cacchiarelli d, d alterio r. Int J Mol Sci. 2021 Feb 11;22(4):1801. doi: 10.3390/ijms22041801. Int J Mol Sci. 2021. PMID: 33670365 Free PMC article.
Single-Cell RNA Sequencing Analysis: A Step-by-Step Overview.
Slovin S, Carissimo A, Panariello F, Grimaldi A, Bouché V, Gambardella G, Cacchiarelli D. Slovin S, et al. Among authors: cacchiarelli d. Methods Mol Biol. 2021;2284:343-365. doi: 10.1007/978-1-0716-1307-8_19. Methods Mol Biol. 2021. PMID: 33835452
Automatic identification of small molecules that promote cell conversion and reprogramming.
Napolitano F, Rapakoulia T, Annunziata P, Hasegawa A, Cardon M, Napolitano S, Vaccaro L, Iuliano A, Wanderlingh LG, Kasukawa T, Medina DL, Cacchiarelli D, Gao X, di Bernardo D, Arner E. Napolitano F, et al. Among authors: cacchiarelli d. Stem Cell Reports. 2021 May 11;16(5):1381-1390. doi: 10.1016/j.stemcr.2021.03.028. Epub 2021 Apr 22. Stem Cell Reports. 2021. PMID: 33891873 Free PMC article.
57 results