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Page 1
Extracellular matrix hydrogel derived from decellularized tissues enables endodermal organoid culture.
Giobbe GG, Crowley C, Luni C, Campinoti S, Khedr M, Kretzschmar K, De Santis MM, Zambaiti E, Michielin F, Meran L, Hu Q, van Son G, Urbani L, Manfredi A, Giomo M, Eaton S, Cacchiarelli D, Li VSW, Clevers H, Bonfanti P, Elvassore N, De Coppi P. Giobbe GG, et al. Among authors: cacchiarelli d. Nat Commun. 2019 Dec 11;10(1):5658. doi: 10.1038/s41467-019-13605-4. Nat Commun. 2019. PMID: 31827102 Free PMC article.
The Microfluidic Environment Reveals a Hidden Role of Self-Organizing Extracellular Matrix in Hepatic Commitment and Organoid Formation of hiPSCs.
Michielin F, Giobbe GG, Luni C, Hu Q, Maroni I, Orford MR, Manfredi A, Di Filippo L, David AL, Cacchiarelli D, De Coppi P, Eaton S, Elvassore N. Michielin F, et al. Among authors: cacchiarelli d. Cell Rep. 2020 Dec 1;33(9):108453. doi: 10.1016/j.celrep.2020.108453. Cell Rep. 2020. PMID: 33264615 Free PMC article.
SARS-CoV-2 infection and replication in human gastric organoids.
Giobbe GG, Bonfante F, Jones BC, Gagliano O, Luni C, Zambaiti E, Perin S, Laterza C, Busslinger G, Stuart H, Pagliari M, Bortolami A, Mazzetto E, Manfredi A, Colantuono C, Di Filippo L, Pellegata AF, Panzarin V, Thapar N, Li VSW, Eaton S, Cacchiarelli D, Clevers H, Elvassore N, De Coppi P. Giobbe GG, et al. Among authors: cacchiarelli d. Nat Commun. 2021 Nov 16;12(1):6610. doi: 10.1038/s41467-021-26762-2. Nat Commun. 2021. PMID: 34785679 Free PMC article.
Therapeutic homology-independent targeted integration in retina and liver.
Tornabene P, Ferla R, Llado-Santaeularia M, Centrulo M, Dell'Anno M, Esposito F, Marrocco E, Pone E, Minopoli R, Iodice C, Nusco E, Rossi S, Lyubenova H, Manfredi A, Di Filippo L, Iuliano A, Torella A, Piluso G, Musacchia F, Surace EM, Cacchiarelli D, Nigro V, Auricchio A. Tornabene P, et al. Among authors: cacchiarelli d. Nat Commun. 2022 Apr 12;13(1):1963. doi: 10.1038/s41467-022-29550-8. Nat Commun. 2022. PMID: 35414130 Free PMC article.
3D ECM-rich environment sustains the identity of naive human iPSCs.
Cesare E, Urciuolo A, Stuart HT, Torchio E, Gesualdo A, Laterza C, Gagliano O, Martewicz S, Cui M, Manfredi A, Di Filippo L, Sabatelli P, Squarzoni S, Zorzan I, Betto RM, Martello G, Cacchiarelli D, Luni C, Elvassore N. Cesare E, et al. Among authors: cacchiarelli d. Cell Stem Cell. 2022 Dec 1;29(12):1703-1717.e7. doi: 10.1016/j.stem.2022.11.011. Cell Stem Cell. 2022. PMID: 36459970 Free article.
Cellular population dynamics shape the route to human pluripotency.
Panariello F, Gagliano O, Luni C, Grimaldi A, Angiolillo S, Qin W, Manfredi A, Annunziata P, Slovin S, Vaccaro L, Riccardo S, Bouche V, Dionisi M, Salvi M, Martewicz S, Hu M, Cui M, Stuart H, Laterza C, Baruzzo G, Schiebinger G, Di Camillo B, Cacchiarelli D, Elvassore N. Panariello F, et al. Among authors: cacchiarelli d. Nat Commun. 2023 May 17;14(1):2829. doi: 10.1038/s41467-023-37270-w. Nat Commun. 2023. PMID: 37198156 Free PMC article.
Single-cell guided prenatal derivation of primary fetal epithelial organoids from human amniotic and tracheal fluids.
Gerli MFM, Calà G, Beesley MA, Sina B, Tullie L, Sun KY, Panariello F, Michielin F, Davidson JR, Russo FM, Jones BC, Lee DDH, Savvidis S, Xenakis T, Simcock IC, Straatman-Iwanowska AA, Hirst RA, David AL, O'Callaghan C, Olivo A, Eaton S, Loukogeorgakis SP, Cacchiarelli D, Deprest J, Li VSW, Giobbe GG, De Coppi P. Gerli MFM, et al. Among authors: cacchiarelli d. Nat Med. 2024 Mar;30(3):875-887. doi: 10.1038/s41591-024-02807-z. Epub 2024 Mar 4. Nat Med. 2024. PMID: 38438734 Free PMC article.
Triple Vectors Expand AAV Transfer Capacity in the Retina.
Maddalena A, Tornabene P, Tiberi P, Minopoli R, Manfredi A, Mutarelli M, Rossi S, Simonelli F, Naggert JK, Cacchiarelli D, Auricchio A. Maddalena A, et al. Among authors: cacchiarelli d. Mol Ther. 2018 Feb 7;26(2):524-541. doi: 10.1016/j.ymthe.2017.11.019. Epub 2017 Dec 5. Mol Ther. 2018. PMID: 29292161 Free PMC article.
57 results