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A Stress-Resistant Lipidomic Signature Confers Extreme Longevity to Humans.
Jové M, Naudí A, Gambini J, Borras C, Cabré R, Portero-Otín M, Viña J, Pamplona R. Jové M, et al. Among authors: cabre r. J Gerontol A Biol Sci Med Sci. 2017 Jan;72(1):30-37. doi: 10.1093/gerona/glw048. Epub 2016 Mar 24. J Gerontol A Biol Sci Med Sci. 2017. PMID: 27013396
Plasma long-chain free fatty acids predict mammalian longevity.
Jové M, Naudí A, Aledo JC, Cabré R, Ayala V, Portero-Otin M, Barja G, Pamplona R. Jové M, et al. Among authors: cabre r. Sci Rep. 2013 Nov 28;3:3346. doi: 10.1038/srep03346. Sci Rep. 2013. PMID: 24284984 Free PMC article.
Region-specific vulnerability to lipid peroxidation and evidence of neuronal mechanisms for polyunsaturated fatty acid biosynthesis in the healthy adult human central nervous system.
Naudí A, Cabré R, Dominguez-Gonzalez M, Ayala V, Jové M, Mota-Martorell N, Piñol-Ripoll G, Gil-Villar MP, Rué M, Portero-Otín M, Ferrer I, Pamplona R. Naudí A, et al. Among authors: cabre r. Biochim Biophys Acta Mol Cell Biol Lipids. 2017 May;1862(5):485-495. doi: 10.1016/j.bbalip.2017.02.001. Epub 2017 Feb 7. Biochim Biophys Acta Mol Cell Biol Lipids. 2017. PMID: 28185952
Methionine transsulfuration pathway is upregulated in long-lived humans.
Mota-Martorell N, Jové M, Borrás C, Berdún R, Obis È, Sol J, Cabré R, Pradas I, Galo-Licona JD, Puig J, Viña J, Pamplona R. Mota-Martorell N, et al. Among authors: cabre r. Free Radic Biol Med. 2021 Jan;162:38-52. doi: 10.1016/j.freeradbiomed.2020.11.026. Epub 2020 Nov 30. Free Radic Biol Med. 2021. PMID: 33271279
Rapamycin reverses age-related increases in mitochondrial ROS production at complex I, oxidative stress, accumulation of mtDNA fragments inside nuclear DNA, and lipofuscin level, and increases autophagy, in the liver of middle-aged mice.
Martínez-Cisuelo V, Gómez J, García-Junceda I, Naudí A, Cabré R, Mota-Martorell N, López-Torres M, González-Sánchez M, Pamplona R, Barja G. Martínez-Cisuelo V, et al. Among authors: cabre r. Exp Gerontol. 2016 Oct;83:130-8. doi: 10.1016/j.exger.2016.08.002. Epub 2016 Aug 4. Exp Gerontol. 2016. PMID: 27498120
21 results