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Gas6/Axl pathway is activated in chronic liver disease and its targeting reduces fibrosis via hepatic stellate cell inactivation.
Bárcena C, Stefanovic M, Tutusaus A, Joannas L, Menéndez A, García-Ruiz C, Sancho-Bru P, Marí M, Caballeria J, Rothlin CV, Fernández-Checa JC, de Frutos PG, Morales A. Bárcena C, et al. Among authors: caballeria j. J Hepatol. 2015 Sep;63(3):670-8. doi: 10.1016/j.jhep.2015.04.013. Epub 2015 Apr 20. J Hepatol. 2015. PMID: 25908269 Free PMC article.
ASMase is required for chronic alcohol induced hepatic endoplasmic reticulum stress and mitochondrial cholesterol loading.
Fernandez A, Matias N, Fucho R, Ribas V, Von Montfort C, Nuño N, Baulies A, Martinez L, Tarrats N, Mari M, Colell A, Morales A, Dubuquoy L, Mathurin P, Bataller R, Caballeria J, Elena M, Balsinde J, Kaplowitz N, Garcia-Ruiz C, Fernandez-Checa JC. Fernandez A, et al. Among authors: caballeria j. J Hepatol. 2013 Oct;59(4):805-13. doi: 10.1016/j.jhep.2013.05.023. Epub 2013 May 23. J Hepatol. 2013. PMID: 23707365 Free PMC article.
Pentraxin-3 modulates lipopolysaccharide-induced inflammatory response and attenuates liver injury.
Perea L, Coll M, Sanjurjo L, Blaya D, Taghdouini AE, Rodrigo-Torres D, Altamirano J, Graupera I, Aguilar-Bravo B, Llopis M, Vallverdú J, Caballeria J, van Grunsven LA, Sarrias MR, Ginès P, Sancho-Bru P. Perea L, et al. Among authors: caballeria j. Hepatology. 2017 Sep;66(3):953-968. doi: 10.1002/hep.29215. Epub 2017 Jul 18. Hepatology. 2017. PMID: 28422322 Free PMC article.
Endothelial dysfunction markers predict short-term mortality in patients with severe alcoholic hepatitis.
Blaya D, Rubio-Tomás T, Rodrigo-Torres D, Lozano J, Coll M, Argemi J, Altamirano J, Affò S, Morales-Ibanez O, Gratacós-Ginès J, Pose E, Tanguy M, Issoufaly T, Rautou PE, Bataller R, Caballería J, Sancho-Bru P. Blaya D, et al. Among authors: caballeria j. Hepatol Int. 2021 Aug;15(4):1006-1017. doi: 10.1007/s12072-021-10165-y. Epub 2021 May 5. Hepatol Int. 2021. PMID: 33954832 Free PMC article.
The biliary epithelium gives rise to liver progenitor cells.
Rodrigo-Torres D, Affò S, Coll M, Morales-Ibanez O, Millán C, Blaya D, Alvarez-Guaita A, Rentero C, Lozano JJ, Maestro MA, Solar M, Arroyo V, Caballería J, van Grunsven LA, Enrich C, Ginès P, Bataller R, Sancho-Bru P. Rodrigo-Torres D, et al. Among authors: caballeria j. Hepatology. 2014 Oct;60(4):1367-77. doi: 10.1002/hep.27078. Epub 2014 Aug 21. Hepatology. 2014. PMID: 24700364 Free PMC article.
Mitochondrial GSH replenishment as a potential therapeutic approach for Niemann Pick type C disease.
Torres S, Matías N, Baulies A, Nuñez S, Alarcon-Vila C, Martinez L, Nuño N, Fernandez A, Caballeria J, Levade T, Gonzalez-Franquesa A, Garcia-Rovés P, Balboa E, Zanlungo S, Fabrías G, Casas J, Enrich C, Garcia-Ruiz C, Fernández-Checa JC. Torres S, et al. Among authors: caballeria j. Redox Biol. 2017 Apr;11:60-72. doi: 10.1016/j.redox.2016.11.010. Epub 2016 Nov 20. Redox Biol. 2017. PMID: 27888692 Free PMC article.
Chemokine Receptor Ccr6 Deficiency Alters Hepatic Inflammatory Cell Recruitment and Promotes Liver Inflammation and Fibrosis.
Affò S, Rodrigo-Torres D, Blaya D, Morales-Ibanez O, Coll M, Millán C, Altamirano J, Arroyo V, Caballería J, Bataller R, Ginès P, Sancho-Bru P. Affò S, et al. Among authors: caballeria j. PLoS One. 2015 Dec 21;10(12):e0145147. doi: 10.1371/journal.pone.0145147. eCollection 2015. PLoS One. 2015. PMID: 26691857 Free PMC article.
Ductular Reaction Cells Display an Inflammatory Profile and Recruit Neutrophils in Alcoholic Hepatitis.
Aguilar-Bravo B, Rodrigo-Torres D, Ariño S, Coll M, Pose E, Blaya D, Graupera I, Perea L, Vallverdú J, Rubio-Tomás T, Dubuquoy L, Armengol C, Lo Nigro A, Stärkel P, Mathurin P, Bataller R, Caballería J, José Lozano J, Ginès P, Sancho-Bru P. Aguilar-Bravo B, et al. Among authors: caballeria j. Hepatology. 2019 May;69(5):2180-2195. doi: 10.1002/hep.30472. Epub 2019 Mar 12. Hepatology. 2019. PMID: 30565271 Free PMC article.
Specific contribution of methionine and choline in nutritional nonalcoholic steatohepatitis: impact on mitochondrial S-adenosyl-L-methionine and glutathione.
Caballero F, Fernández A, Matías N, Martínez L, Fucho R, Elena M, Caballeria J, Morales A, Fernández-Checa JC, García-Ruiz C. Caballero F, et al. Among authors: caballeria j. J Biol Chem. 2010 Jun 11;285(24):18528-36. doi: 10.1074/jbc.M109.099333. Epub 2010 Apr 15. J Biol Chem. 2010. PMID: 20395294 Free PMC article.
193 results