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Blood MMP-9 measured at 2 years after lung transplantation as a prognostic biomarker of chronic lung allograft dysfunction.
Tissot A, Durand E, Goronflot T, Coiffard B, Renaud-Picard B, Roux A, Demant X, Mornex JF, Falque L, Salpin M, Le Pavec J, Villeneuve T, Boussaud V, Knoop C, Magnan A, Lair D, Berthelot L, Danger R, Brouard S; COLT consortium. Tissot A, et al. Respir Res. 2024 Feb 9;25(1):88. doi: 10.1186/s12931-024-02707-3. Respir Res. 2024. PMID: 38336710 Free PMC article.
Chronic lung allograft dysfunction is associated with an early increase of circulating cytotoxic CD4+CD57+ILT2+ T cells, selectively inhibited by the immune check-point HLA-G.
Brugière O, Mouren D, Trichereau J, Vallée A, Kuzniak I, Hirschi S, Renaud-Picard B, Reynaud-Gaubert M, Nieves A, Bunel V, Messika J, Demant X, Macey J, Le Pavec J, Dauriat G, Saint-Raymond C, Falque L, Mornex JF, Tissot A, Foureau A, Borgne Krams AL, Bousseau V, Magnan A, Picard C, Roux A, Carosella E, LeMaoult J, Rouas-Freiss N; COLT Consortium. Brugière O, et al. J Heart Lung Transplant. 2022 May;41(5):626-640. doi: 10.1016/j.healun.2022.01.013. Epub 2022 Jan 24. J Heart Lung Transplant. 2022. PMID: 35181243
Overexpression of the MSK1 Kinase in Patients With Chronic Lung Allograft Dysfunction and Its Confirmed Role in a Murine Model.
Nemska S, Daubeuf F, Obrecht A, Israel-Biet D, Stern M, Kessler R, Roux A, Tavakoli R, Villa P, Tissot A, Danger R, Reber L, Durand E, Foureau A, Brouard S, Magnan A, Frossard N; COLT consortium. Nemska S, et al. Transplantation. 2021 Jun 1;105(6):1212-1224. doi: 10.1097/TP.0000000000003606. Transplantation. 2021. PMID: 33560725
Systematic analysis of blood cell transcriptome in end-stage chronic respiratory diseases.
Chesné J, Danger R, Botturi K, Reynaud-Gaubert M, Mussot S, Stern M, Danner-Boucher I, Mornex JF, Pison C, Dromer C, Kessler R, Dahan M, Brugière O, Le Pavec J, Perros F, Humbert M, Gomez C, Brouard S, Magnan A; COLT Consortium. Chesné J, et al. PLoS One. 2014 Oct 20;9(10):e109291. doi: 10.1371/journal.pone.0109291. eCollection 2014. PLoS One. 2014. PMID: 25329529 Free PMC article.
Donor Club Cell Secretory Protein G38A Polymorphism Is Associated With a Decreased Risk of Primary Graft Dysfunction in the French Cohort in Lung Transplantation.
Hin A, Kannengiesser C, Roussel A, Renaud-Picard B, Roux A, Reynaud-Gaubert M, Claustre J, Tissot A, Guillemain R, Mornex JF, Mussot S, Dromer C, Dahan M, Brugière O, Mercier O, Borie R, Pretolani M, Castier Y, Mordant P; COLT Consortium. Hin A, et al. Transplantation. 2018 Aug;102(8):1382-1390. doi: 10.1097/TP.0000000000002143. Transplantation. 2018. PMID: 29470356
T Cells Promote Bronchial Epithelial Cell Secretion of Matrix Metalloproteinase-9 via a C-C Chemokine Receptor Type 2 Pathway: Implications for Chronic Lung Allograft Dysfunction.
Pain M, Royer PJ, Loy J, Girardeau A, Tissot A, Lacoste P, Roux A, Reynaud-Gaubert M, Kessler R, Mussot S, Dromer C, Brugière O, Mornex JF, Guillemain R, Dahan M, Knoop C, Botturi K, Pison C, Danger R, Brouard S, Magnan A; COLT Consortium. Pain M, et al. Am J Transplant. 2017 Jun;17(6):1502-1514. doi: 10.1111/ajt.14166. Epub 2017 Jan 23. Am J Transplant. 2017. PMID: 27982503 Free article.