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Page 1
Acetylation reprograms MITF target selectivity and residence time.
Louphrasitthiphol P, Loffreda A, Pogenberg V, Picaud S, Schepsky A, Friedrichsen H, Zeng Z, Lashgari A, Thomas B, Patton EE, Wilmanns M, Filippakopoulos P, Lambert JP, Steingrímsson E, Mazza D, Goding CR. Louphrasitthiphol P, et al. Nat Commun. 2023 Sep 28;14(1):6051. doi: 10.1038/s41467-023-41793-7. Nat Commun. 2023. PMID: 37770430 Free PMC article.
Hypoxia-induced SETX links replication stress with the unfolded protein response.
Ramachandran S, Ma TS, Griffin J, Ng N, Foskolou IP, Hwang MS, Victori P, Cheng WC, Buffa FM, Leszczynska KB, El-Khamisy SF, Gromak N, Hammond EM. Ramachandran S, et al. Nat Commun. 2021 Jun 17;12(1):3686. doi: 10.1038/s41467-021-24066-z. Nat Commun. 2021. PMID: 34140498 Free PMC article.
BRAF/MAPK and GSK3 signaling converges to control MITF nuclear export.
Ngeow KC, Friedrichsen HJ, Li L, Zeng Z, Andrews S, Volpon L, Brunsdon H, Berridge G, Picaud S, Fischer R, Lisle R, Knapp S, Filippakopoulos P, Knowles H, Steingrímsson E, Borden KLB, Patton EE, Goding CR. Ngeow KC, et al. Proc Natl Acad Sci U S A. 2018 Sep 11;115(37):E8668-E8677. doi: 10.1073/pnas.1810498115. Epub 2018 Aug 27. Proc Natl Acad Sci U S A. 2018. PMID: 30150413 Free PMC article.
Challenges to DNA replication in hypoxic conditions.
Ng N, Purshouse K, Foskolou IP, Olcina MM, Hammond EM. Ng N, et al. FEBS J. 2018 May;285(9):1563-1571. doi: 10.1111/febs.14377. Epub 2018 Jan 12. FEBS J. 2018. PMID: 29288533 Free article. Review.
Measuring DNA Replication in Hypoxic Conditions.
Foskolou IP, Biasoli D, Olcina MM, Hammond EM. Foskolou IP, et al. Adv Exp Med Biol. 2016;899:11-25. doi: 10.1007/978-3-319-26666-4_2. Adv Exp Med Biol. 2016. PMID: 27325259