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Liver-specific ablation of insulin-degrading enzyme causes hepatic insulin resistance and glucose intolerance, without affecting insulin clearance in mice.
Villa-Pérez P, Merino B, Fernández-Díaz CM, Cidad P, Lobatón CD, Moreno A, Muturi HT, Ghadieh HE, Najjar SM, Leissring MA, Cózar-Castellano I, Perdomo G. Villa-Pérez P, et al. Metabolism. 2018 Nov;88:1-11. doi: 10.1016/j.metabol.2018.08.001. Epub 2018 Aug 8. Metabolism. 2018. PMID: 30098324 Free PMC article.
Increased Aβ production prompts the onset of glucose intolerance and insulin resistance.
Jiménez-Palomares M, Ramos-Rodríguez JJ, López-Acosta JF, Pacheco-Herrero M, Lechuga-Sancho AM, Perdomo G, García-Alloza M, Cózar-Castellano I. Jiménez-Palomares M, et al. Am J Physiol Endocrinol Metab. 2012 Jun 1;302(11):E1373-80. doi: 10.1152/ajpendo.00500.2011. Epub 2012 Mar 13. Am J Physiol Endocrinol Metab. 2012. PMID: 22414803 Free article.
Differential central pathology and cognitive impairment in pre-diabetic and diabetic mice.
Ramos-Rodriguez JJ, Ortiz O, Jimenez-Palomares M, Kay KR, Berrocoso E, Murillo-Carretero MI, Perdomo G, Spires-Jones T, Cozar-Castellano I, Lechuga-Sancho AM, Garcia-Alloza M. Ramos-Rodriguez JJ, et al. Psychoneuroendocrinology. 2013 Nov;38(11):2462-75. doi: 10.1016/j.psyneuen.2013.05.010. Epub 2013 Jun 21. Psychoneuroendocrinology. 2013. PMID: 23790682
Cyclin C stimulates β-cell proliferation in rat and human pancreatic β-cells.
Jiménez-Palomares M, López-Acosta JF, Villa-Pérez P, Moreno-Amador JL, Muñoz-Barrera J, Fernández-Luis S, Heras-Pozas B, Perdomo G, Bernal-Mizrachi E, Cózar-Castellano I. Jiménez-Palomares M, et al. Am J Physiol Endocrinol Metab. 2015 Mar 15;308(6):E450-9. doi: 10.1152/ajpendo.00260.2014. Epub 2015 Jan 6. Am J Physiol Endocrinol Metab. 2015. PMID: 25564474 Free PMC article.
53 results