Liquid-liquid miscibility gaps in drug-water binary systems: crystal structure and thermodynamic properties of prilocaine and the temperature-composition phase diagram of the prilocaine-water system.
Rietveld IB, Perrin MA, Toscani S, Barrio M, Nicolai B, Tamarit JL, Ceolin R.
Rietveld IB, et al. Among authors: ceolin r.
Mol Pharm. 2013 Apr 1;10(4):1332-9. doi: 10.1021/mp300542k. Epub 2013 Mar 18.
Mol Pharm. 2013.
PMID: 23339548
Similar behavior has been reported for the binary system lidocaine-water (Ceolin, R.; et al. J. Pharm. Sci. 2010, 99 (6), 2756-2765). In the ternary mixture, the combination of the monotectic equilibrium and the above-mentioned eutectic equilibrium between prilocain …
Similar behavior has been reported for the binary system lidocaine-water (Ceolin, R.; et al. J. Pharm. Sci. 2010, 99 (6), 2756 …