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Page 1
Rare, convergent antibodies targeting the stem helix broadly neutralize diverse betacoronaviruses.
Dacon C, Peng L, Lin TH, Tucker C, Lee CD, Cong Y, Wang L, Purser L, Cooper AJR, Williams JK, Pyo CW, Yuan M, Kosik I, Hu Z, Zhao M, Mohan D, Peterson M, Skinner J, Dixit S, Kollins E, Huzella L, Perry D, Byrum R, Lembirik S, Murphy M, Zhang Y, Yang ES, Chen M, Leung K, Weinberg RS, Pegu A, Geraghty DE, Davidson E, Doranz BJ, Douagi I, Moir S, Yewdell JW, Schmaljohn C, Crompton PD, Mascola JR, Holbrook MR, Nemazee D, Wilson IA, Tan J. Dacon C, et al. Among authors: byrum r. Cell Host Microbe. 2023 Jan 11;31(1):97-111.e12. doi: 10.1016/j.chom.2022.10.010. Epub 2022 Nov 7. Cell Host Microbe. 2023. PMID: 36347257 Free PMC article.
The Use of Large-Particle Aerosol Exposure to Nipah Virus to Mimic Human Neurological Disease Manifestations in the African Green Monkey.
Lee JH, Hammoud DA, Cong Y, Huzella LM, Castro MA, Solomon J, Laux J, Lackemeyer M, Bohannon JK, Rojas O, Byrum R, Adams R, Ragland D, St Claire M, Munster V, Holbrook MR. Lee JH, et al. Among authors: byrum r. J Infect Dis. 2020 May 11;221(Suppl 4):S419-S430. doi: 10.1093/infdis/jiz502. J Infect Dis. 2020. PMID: 31687756 Free PMC article.
Expanded Histopathology and Tropism of Ebola Virus in the Rhesus Macaque Model: Potential for Sexual Transmission, Altered Adrenomedullary Hormone Production, and Early Viral Replication in Liver.
Liu DX, Cooper TK, Perry DL, Huzella LM, Hischak AMW, Hart RJ, Isic N, Byrum R, Ragland D, St Claire M, Cooper K, Reeder R, Logue J, Jahrling PB, Holbrook MR, Bennett RS, Hensley LE. Liu DX, et al. Among authors: byrum r. Am J Pathol. 2022 Jan;192(1):121-129. doi: 10.1016/j.ajpath.2021.09.009. Epub 2021 Oct 6. Am J Pathol. 2022. PMID: 34626576 Free PMC article.
Broadly neutralizing antibodies target the coronavirus fusion peptide.
Dacon C, Tucker C, Peng L, Lee CD, Lin TH, Yuan M, Cong Y, Wang L, Purser L, Williams JK, Pyo CW, Kosik I, Hu Z, Zhao M, Mohan D, Cooper AJR, Peterson M, Skinner J, Dixit S, Kollins E, Huzella L, Perry D, Byrum R, Lembirik S, Drawbaugh D, Eaton B, Zhang Y, Yang ES, Chen M, Leung K, Weinberg RS, Pegu A, Geraghty DE, Davidson E, Douagi I, Moir S, Yewdell JW, Schmaljohn C, Crompton PD, Holbrook MR, Nemazee D, Mascola JR, Wilson IA, Tan J. Dacon C, et al. Among authors: byrum r. Science. 2022 Aug 12;377(6607):728-735. doi: 10.1126/science.abq3773. Epub 2022 Jul 12. Science. 2022. PMID: 35857439 Free PMC article.
Persistent intraocular Ebola virus RNA is associated with severe uveitis in a convalescent rhesus monkey.
Worwa G, Cooper TK, Yeh S, Shantha JG, Hischak AMW, Klim SE, Byrum R, Kurtz JR, Anthony SM, Aiosa NM, Ragland D, Lee JH, Claire MS, Davis C, Ahmed R, Holbrook MR, Kuhn JH, Saphire EO, Crozier I. Worwa G, et al. Among authors: byrum r. Commun Biol. 2022 Nov 9;5(1):1204. doi: 10.1038/s42003-022-04158-2. Commun Biol. 2022. PMID: 36352100 Free PMC article.
Evaluation of a panel of therapeutic antibody clinical candidates for efficacy against SARS-CoV-2 in Syrian hamsters.
Cong Y, Mucker EM, Perry DL, Dixit S, Kollins E, Byrum R, Huzella L, Kim R, Josleyn M, Kwilas S, Stefan C, Shoemaker CJ, Koehler J, Coyne S, Delp K, Liang J, Drawbaugh D, Hischak A, Hart R, Postnikova E, Vaughan N, Asher J, St Claire M, Hanson J, Schmaljohn C, Eakin AE, Hooper JW, Holbrook MR. Cong Y, et al. Among authors: byrum r. Antiviral Res. 2023 May;213:105589. doi: 10.1016/j.antiviral.2023.105589. Epub 2023 Mar 30. Antiviral Res. 2023. PMID: 37003305 Free PMC article.
Longitudinal analyses using 18F-Fluorodeoxyglucose positron emission tomography with computed tomography as a measure of COVID-19 severity in the aged, young, and humanized ACE2 SARS-CoV-2 hamster models.
Cong Y, Lee JH, Perry DL, Cooper K, Wang H, Dixit S, Liu DX, Feuerstein IM, Solomon J, Bartos C, Seidel J, Hammoud DA, Adams R, Anthony SM, Liang J, Schuko N, Li R, Liu Y, Wang Z, Tarbet EB, Hischak AMW, Hart R, Isic N, Burdette T, Drawbaugh D, Huzella LM, Byrum R, Ragland D, St Claire MC, Wada J, Kurtz JR, Hensley LE, Schmaljohn CS, Holbrook MR, Johnson RF. Cong Y, et al. Among authors: byrum r. Antiviral Res. 2023 Jun;214:105605. doi: 10.1016/j.antiviral.2023.105605. Epub 2023 Apr 15. Antiviral Res. 2023. PMID: 37068595 Free PMC article.
Ebola Virus Disease Features Hemophagocytic Lymphohistiocytosis/Macrophage Activation Syndrome in the Rhesus Macaque Model.
Liu DX, Pahar B, Cooper TK, Perry DL, Xu H, Huzella LM, Adams RD, Hischak AMW, Hart RJ, Bernbaum R, Rivera D, Anthony S, Claire MS, Byrum R, Cooper K, Reeder R, Kurtz J, Hadley K, Wada J, Crozier I, Worwa G, Bennett RS, Warren T, Holbrook MR, Schmaljohn CS, Hensley LE. Liu DX, et al. Among authors: byrum r. J Infect Dis. 2023 Aug 16;228(4):371-382. doi: 10.1093/infdis/jiad203. J Infect Dis. 2023. PMID: 37279544
Clinical and Immunologic Correlates of Vasodilatory Shock Among Ebola Virus-Infected Nonhuman Primates in a Critical Care Model.
Stein SR, Platt AP, Teague HL, Anthony SM, Reeder RJ, Cooper K, Byrum R, Drawbaugh DJ 2nd, Liu DX, Burdette TL, Hadley K, Barr B, Warner S, Rodriguez-Hernandez F, Johnson C, Stanek P, Hischak J, Kendall H, Huzella LM, Strich JR, Herbert R, St Claire M, Vannella KM, Holbrook MR, Chertow DS. Stein SR, et al. Among authors: byrum r. J Infect Dis. 2023 Nov 13;228(Suppl 7):S635-S647. doi: 10.1093/infdis/jiad374. J Infect Dis. 2023. PMID: 37652048 Free PMC article.
59 results