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Structure-based design of prefusion-stabilized SARS-CoV-2 spikes.
Hsieh CL, Goldsmith JA, Schaub JM, DiVenere AM, Kuo HC, Javanmardi K, Le KC, Wrapp D, Lee AG, Liu Y, Chou CW, Byrne PO, Hjorth CK, Johnson NV, Ludes-Meyers J, Nguyen AW, Park J, Wang N, Amengor D, Lavinder JJ, Ippolito GC, Maynard JA, Finkelstein IJ, McLellan JS. Hsieh CL, et al. Among authors: byrne po. Science. 2020 Sep 18;369(6510):1501-1505. doi: 10.1126/science.abd0826. Epub 2020 Jul 23. Science. 2020. PMID: 32703906 Free PMC article.
Structure-based Design of Prefusion-stabilized SARS-CoV-2 Spikes.
Hsieh CL, Goldsmith JA, Schaub JM, DiVenere AM, Kuo HC, Javanmardi K, Le KC, Wrapp D, Lee AG, Liu Y, Chou CW, Byrne PO, Hjorth CK, Johnson NV, Ludes-Meyers J, Nguyen AW, Park J, Wang N, Amengor D, Maynard JA, Finkelstein IJ, McLellan JS. Hsieh CL, et al. Among authors: byrne po. bioRxiv [Preprint]. 2020 May 30:2020.05.30.125484. doi: 10.1101/2020.05.30.125484. bioRxiv. 2020. PMID: 32577660 Free PMC article. Updated. Preprint.
Expression and characterization of SARS-CoV-2 spike proteins.
Schaub JM, Chou CW, Kuo HC, Javanmardi K, Hsieh CL, Goldsmith J, DiVenere AM, Le KC, Wrapp D, Byrne PO, Hjorth CK, Johnson NV, Ludes-Meyers J, Nguyen AW, Wang N, Lavinder JJ, Ippolito GC, Maynard JA, McLellan JS, Finkelstein IJ. Schaub JM, et al. Among authors: byrne po. Nat Protoc. 2021 Nov;16(11):5339-5356. doi: 10.1038/s41596-021-00623-0. Epub 2021 Oct 5. Nat Protoc. 2021. PMID: 34611365 Free PMC article. Review.
IgG-like bispecific antibodies with potent and synergistic neutralization against circulating SARS-CoV-2 variants of concern.
Chang MR, Tomasovic L, Kuzmina NA, Ronk AJ, Byrne PO, Johnson R, Storm N, Olmedillas E, Hou YJ, Schäfer A, Leist SR, Tse LV, Ke H, Coherd C, Nguyen K, Kamkaew M, Honko A, Zhu Q, Alter G, Saphire EO, McLellan JS, Griffiths A, Baric RS, Bukreyev A, Marasco WA. Chang MR, et al. Among authors: byrne po. Nat Commun. 2022 Oct 3;13(1):5814. doi: 10.1038/s41467-022-33030-4. Nat Commun. 2022. PMID: 36192374 Free PMC article.
Prefusion stabilization of the Hendra and Langya virus F proteins.
Byrne PO, Blade EG, Fisher BE, Ambrozak DR, Ramamohan AR, Graham BS, Loomis RJ, McLellan JS. Byrne PO, et al. J Virol. 2024 Feb 20;98(2):e0137223. doi: 10.1128/jvi.01372-23. Epub 2024 Jan 12. J Virol. 2024. PMID: 38214525 Free PMC article.
A single ligand is sufficient to activate EGFR dimers.
Liu P, Cleveland TE 4th, Bouyain S, Byrne PO, Longo PA, Leahy DJ. Liu P, et al. Among authors: byrne po. Proc Natl Acad Sci U S A. 2012 Jul 3;109(27):10861-6. doi: 10.1073/pnas.1201114109. Epub 2012 Jun 14. Proc Natl Acad Sci U S A. 2012. PMID: 22699492 Free PMC article.
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