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Activity of Imipenem, Meropenem, Cefepime, and Sulbactam in Combination with the β-Lactamase Inhibitor LN-1-255 against Acinetobacter spp.
Lasarte-Monterrubio C, Vázquez-Ucha JC, Maneiro M, Arca-Suárez J, Alonso I, Guijarro-Sánchez P, Buynak JD, Bou G, González-Bello C, Beceiro A. Lasarte-Monterrubio C, et al. Among authors: buynak jd. Antibiotics (Basel). 2021 Feb 20;10(2):210. doi: 10.3390/antibiotics10020210. Antibiotics (Basel). 2021. PMID: 33672671 Free PMC article.
Design, synthesis, and crystal structures of 6-alkylidene-2'-substituted penicillanic acid sulfones as potent inhibitors of Acinetobacter baumannii OXA-24 carbapenemase.
Bou G, Santillana E, Sheri A, Beceiro A, Sampson JM, Kalp M, Bethel CR, Distler AM, Drawz SM, Pagadala SR, van den Akker F, Bonomo RA, Romero A, Buynak JD. Bou G, et al. Among authors: buynak jd. J Am Chem Soc. 2010 Sep 29;132(38):13320-31. doi: 10.1021/ja104092z. J Am Chem Soc. 2010. PMID: 20822105 Free PMC article.
LN-1-255, a penicillanic acid sulfone able to inhibit the class D carbapenemase OXA-48.
Vallejo JA, Martínez-Guitián M, Vázquez-Ucha JC, González-Bello C, Poza M, Buynak JD, Bethel CR, Bonomo RA, Bou G, Beceiro A. Vallejo JA, et al. Among authors: buynak jd. J Antimicrob Chemother. 2016 Aug;71(8):2171-80. doi: 10.1093/jac/dkw105. Epub 2016 Apr 28. J Antimicrob Chemother. 2016. PMID: 27125555 Free PMC article.
Therapeutic Efficacy of LN-1-255 in Combination with Imipenem in Severe Infection Caused by Carbapenem-Resistant Acinetobacter baumannii.
Vázquez-Ucha JC, Martínez-Guitián M, Maneiro M, Conde-Pérez K, Álvarez-Fraga L, Torrens G, Oliver A, Buynak JD, Bonomo RA, Bou G, González-Bello C, Poza M, Beceiro A. Vázquez-Ucha JC, et al. Among authors: buynak jd. Antimicrob Agents Chemother. 2019 Sep 23;63(10):e01092-19. doi: 10.1128/AAC.01092-19. Print 2019 Oct. Antimicrob Agents Chemother. 2019. PMID: 31383666 Free PMC article.
53 results