Buynak JD - Search Results

1

Virtual Screening and Experimental Testing of B1 Metallo-β-lactamase Inhibitors.

Kang JS, Zhang AL, Faheem M, Zhang CJ, Ai N, Buynak JD, Welsh WJ, Oelschlaeger P. Kang JS, et al. Among authors: buynak jd. J Chem Inf Model. 2018 Sep 24;58(9):1902-1914. doi: 10.1021/acs.jcim.8b00133. Epub 2018 Aug 29. J Chem Inf Model. 2018. PMID: 30107123 Free PMC article.

2

Cephalosporin-derived inhibitors of beta-lactamase. Part 4: The C3 substituent.

Buynak JD, Vogeti L, Doppalapudi VR, Solomon GM, Chen H. Buynak JD, et al. Bioorg Med Chem Lett. 2002 Jun 17;12(12):1663-6. doi: 10.1016/s0960-894x(02)00205-6. Bioorg Med Chem Lett. 2002. PMID: 12039585

3

Penicillin-derived inhibitors that simultaneously target both metallo- and serine-beta-lactamases.

Buynak JD, Chen H, Vogeti L, Gadhachanda VR, Buchanan CA, Palzkill T, Shaw RW, Spencer J, Walsh TR. Buynak JD, et al. Bioorg Med Chem Lett. 2004 Mar 8;14(5):1299-304. doi: 10.1016/j.bmcl.2003.12.037. Bioorg Med Chem Lett. 2004. PMID: 14980686

4

The discovery and development of modified penicillin- and cephalosporin-derived beta-lactamase inhibitors.

Buynak JD. Buynak JD. Curr Med Chem. 2004 Jul;11(14):1951-64. doi: 10.2174/0929867043364847. Curr Med Chem. 2004. PMID: 15279575 Review.

5

β-Lactamase inhibitors: a review of the patent literature (2010 - 2013).

Buynak JD. Buynak JD. Expert Opin Ther Pat. 2013 Nov;23(11):1469-81. doi: 10.1517/13543776.2013.831071. Epub 2013 Aug 23. Expert Opin Ther Pat. 2013. PMID: 23967802 Review.

6

Meropenem and chromacef intermediates observed in IMP-25 metallo-β-lactamase-catalyzed hydrolysis.

Oelschlaeger P, Aitha M, Yang H, Kang JS, Zhang AL, Liu EM, Buynak JD, Crowder MW. Oelschlaeger P, et al. Among authors: buynak jd. Antimicrob Agents Chemother. 2015 Jul;59(7):4326-30. doi: 10.1128/AAC.04409-14. Epub 2015 Apr 27. Antimicrob Agents Chemother. 2015. PMID: 25918145 Free PMC article.

7

Triethysilyl Enol Ethers in the Synthesis of Carbapenem Precursors.

Nguyen TQ, Chai W, Gu J, Cook K, Kim E, Goetz S, Farni Z, Chepuru M, Cox M, Nguyen P, Raja H, Magistrado P, Michael F, Oelschlaeger P, Buynak JD. Nguyen TQ, et al. Among authors: buynak jd. Tetrahedron Lett. 2015 Jun 3;56(23):3385-3389. doi: 10.1016/j.tetlet.2015.01.025. Tetrahedron Lett. 2015. PMID: 26034332 Free PMC article.

8

Functionalizing the γ-Position of α-Diazo-β-ketoesters.

Nguyen TQ, Alqurafi M, Edwards C, Nguyen P, Kim J, Casco S, Bennet M, Chiang C, Lohry M, Cox M, Meshram B, Le D, Kim E, Smriti S, Oelschlaeger P, Buynak JD. Nguyen TQ, et al. Among authors: buynak jd. Tetrahedron Lett. 2016 Jun 27;57(30):3330-3333. doi: 10.1016/j.tetlet.2016.06.065. Epub 2016 Jun 16. Tetrahedron Lett. 2016. PMID: 27956752 Free PMC article.

9

Atypically Modified Carbapenem Antibiotics Display Improved Antimycobacterial Activity in the Absence of β-Lactamase Inhibitors.

Gupta R, Al-Kharji NMSA, Alqurafi MA, Nguyen TQ, Chai W, Quan P, Malhotra R, Simcox BS, Mortimer P, Brammer Basta LA, Rohde KH, Buynak JD. Gupta R, et al. Among authors: buynak jd. ACS Infect Dis. 2021 Aug 13;7(8):2425-2436. doi: 10.1021/acsinfecdis.1c00185. Epub 2021 Jun 30. ACS Infect Dis. 2021. PMID: 34191496 Free PMC article.

10

Synthesis and biological activity of 7-alkylidenecephems.

Buynak JD, Wu K, Bachmann B, Khasnis D, Hua L, Nguyen HK, Carver CL. Buynak JD, et al. J Med Chem. 1995 Mar 17;38(6):1022-34. doi: 10.1021/jm00006a022. J Med Chem. 1995. PMID: 7699694

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